caa a22 4500 388112417 CHVBK 20180307125357.0 cr unu---uuuuu 161130e199903 xx s 000 0 eng 10.1017/S0022149X9900030X doi S0022149X9900030X pii (NATIONALLICENCE)cambridge-10.1017/S0022149X9900030X Partial cross protection against Ichthyophthirius multifiliis in Gyrodactylus derjavini immunized rainbow trout [Elektronische Daten] Partial cross protection against a skin-parasitic ciliate has been recorded in rainbow trout previously immunized with an ectoparasitic platyhelminth. The susceptibility to infection by Ichthyophthirius multifiliis differed significantly between naive and Gyrodactylus derjavini immunized rainbow trout. Fish partly immune to the ectoparasitic monogenean G. derjavini became less infected and experienced lower mortality than naive fish when exposed to I. multifiliisinfections. In vitro studies on immobilization of theronts using decomplemented (heat-inactivated) serum from G. derjavini immune or non-immune hosts showed no immobilization. However, untreated serum from both immune and non-immune fish containing intact complement immobilized theronts (titre 128-256). In addition, non-specific priming of the host response with interleukin (IL-1), bacterial lipopolysaccharide (LPS), concanavalin A (Con A) or mannan did confer a partial resistance to I. multifiliis infection. This will suggest that non-specific factors including complement could be partly responsible for the host response against infections with this ciliate. Cambridge University Press Buchmann K. Department of Veterinary Microbiology Section of Fish Diseases, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark Lindenstrøm T. Department of Veterinary Microbiology Section of Fish Diseases, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark Sigh J. Department of Veterinary Microbiology Section of Fish Diseases, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark Journal of Helminthology Cambridge University Press 73/3(1999-03), 189-195 0022-149X 73:3<189 1999 73 JHL https://doi.org/10.1017/S0022149X9900030X text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022149X9900030X text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Buchmann K. Department of Veterinary Microbiology Section of Fish Diseases, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark NATIONALLICENCE 700 1- Lindenstrøm T. Department of Veterinary Microbiology Section of Fish Diseases, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark NATIONALLICENCE 700 1- Sigh J. Department of Veterinary Microbiology Section of Fish Diseases, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark NATIONALLICENCE 773 0- Journal of Helminthology Cambridge University Press 73/3(1999-03), 189-195 0022-149X 73:3<189 1999 73 JHL CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge