caa a22 4500 388112778 CHVBK 20180307125358.0 cr unu---uuuuu 161130e199904 xx s 000 0 eng 10.1017/S0022149X99000530 doi S0022149X99000530 pii (NATIONALLICENCE)cambridge-10.1017/S0022149X99000530 Larval toxocariasis and its clinical manifestation in childhood in the Slovak Republic [Elektronische Daten] Results are presented of 90 children aged 1-15 years hospitalized with toxocariasis. Blood count analysis and laboratory examination were done by routine clinical laboratory methods. Anti-Toxocara antibodies were detected in the serum of patients using an ELISA method. Demographic analysis of the children's families exposed to the risk of disease allowed estimation of age-specific rates for clinical toxocariasis. The probability of toxocaral infection and the intensity of its clinical manifestations in children are determined by the epidemiology of this zoonosis and by the risk factors in the family. The presence of high titres of specific IgG antibodies in all age categories correlates with the clinical manifestations of toxocariasis. The highest admission rate is in the age categories of 3-5 years (43.3%) and 6-10 years (36.7%). Laboratory findings show that the most conspicuous changes occur in the age category 1-5 years. The high percentage of seropositive dog-keeping and puppy-breeding families and the possibility of infection with repeated doses of larvae stimulate eosinophilia, which prevails in children under the age of five years. We present the percentage of patients whose parameters showed deviations from the reference values for a particular age category. Analyses of laboratory indices and of clinical manifestations will contribute to the accuracy of diagnosis and effectiveness of treatment of this disease. Cambridge University Press Kinčeková J. Parasitological Institute of the Slovak Academy of Sciences, Hlinkova 3, 040 01 Kosice, Slovak Republic Reiterová K. Parasitological Institute of the Slovak Academy of Sciences, Hlinkova 3, 040 01 Kosice, Slovak Republic Dubinský P. Parasitological Institute of the Slovak Academy of Sciences, Hlinkova 3, 040 01 Kosice, Slovak Republic Journal of Helminthology Cambridge University Press 73/4(1999-04), 323-328 0022-149X 73:4<323 1999 73 JHL https://doi.org/10.1017/S0022149X99000530 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022149X99000530 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kinčeková J. Parasitological Institute of the Slovak Academy of Sciences, Hlinkova 3, 040 01 Kosice, Slovak Republic NATIONALLICENCE 700 1- Reiterová K. Parasitological Institute of the Slovak Academy of Sciences, Hlinkova 3, 040 01 Kosice, Slovak Republic NATIONALLICENCE 700 1- Dubinský P. Parasitological Institute of the Slovak Academy of Sciences, Hlinkova 3, 040 01 Kosice, Slovak Republic NATIONALLICENCE 773 0- Journal of Helminthology Cambridge University Press 73/4(1999-04), 323-328 0022-149X 73:4<323 1999 73 JHL CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge