caa a22 4500 38811519X CHVBK 20180307125405.0 cr unu---uuuuu 161130e199909 xx s 000 0 eng 10.1017/S1047951100005369 doi S1047951100005369 pii (NATIONALLICENCE)cambridge-10.1017/S1047951100005369 Transcatheter closure as standard treatment for most interatrial defects: experience in 200 patients treated with the Amplatzer ™ Septal Occluder [Elektronische Daten] To judge whether an Amplatzer™ Septal Occluder can be used as standard therapy instead of surgery for closure of atrial septal defects we report our experiences in 200 patients. Of these patients, 127 had an atrial septal defect with haemodynamically significant left-to-right shunt, 68 patients a persistent oval foramen after presumed paradoxical embolism, and 5 had a fenestration after Fontan-repair. Mean age was 29.8 years (0.8 to 77.7 years). Body weight ranged from 6.9 to 120.0 kg (mean 51.5 kg). After diagnostic cardiac catheterization, and balloon-sizing of the defect, we implanted Amplatzer™ Septal Occluders with stents of 4 to 28 mm diameter. Follow-up studies were obtained after 48hours, and one, six, and twelve months. Transcatheter closure of the atrial septal defect proved successful in all without any relevant residual shunts. In particular, complete closure was achieved in all patients after presumed paradoxical embolism. The mean period of follow-up is 9-5 months, with a range from 0.4 to 23.5 months, giving a total of 1898 patient months. The occlusion rate after three month was 98.1°. A trivial haemodynamically insignificant residual shunt remained in 1.9° of the patients. Fluoroscopy times ranged from 0 to 43.5 minutes, with a median of 8.7 minutes. The excellent results in the short and medium term in children and adults have resulted in using this device routinely at the present time for closure of central atrial septal defects up to a diameter of 28 mm. Final judgement, however, is only possible after long-term follow-up. Copyright © Cambridge University Press 1999 Atrial septal defect nationallicence interventional cardiology nationallicence transcatheter closure nationallicence Amplatzer™ Septal Occluder nationallicence Berger Felix Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany Ewert Peter Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany Boöjrnstad Per G. Rikshospitalet, Oslo, Norway Dähnert Ingo Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany Krings Gregor Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany Brilla-Austenat Ira Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany Vogel Michael Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany Lange Peter E. Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany Cardiology in the Young Cambridge University Press 9/5(1999-09), 468-473 1047-9511 9:5<468 1999 9 CTY https://doi.org/10.1017/S1047951100005369 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S1047951100005369 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Berger Felix Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany NATIONALLICENCE 700 1- Ewert Peter Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany NATIONALLICENCE 700 1- Boöjrnstad Per G. Rikshospitalet, Oslo, Norway NATIONALLICENCE 700 1- Dähnert Ingo Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany NATIONALLICENCE 700 1- Krings Gregor Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany NATIONALLICENCE 700 1- Brilla-Austenat Ira Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany NATIONALLICENCE 700 1- Vogel Michael Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany NATIONALLICENCE 700 1- Lange Peter E. Klinik für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany NATIONALLICENCE 773 0- Cardiology in the Young Cambridge University Press 9/5(1999-09), 468-473 1047-9511 9:5<468 1999 9 CTY CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge