caa a22 4500 388115467 CHVBK 20180307125405.0 cr unu---uuuuu 161130e199905 xx s 000 0 eng 10.1017/S1047951100004959 doi S1047951100004959 pii (NATIONALLICENCE)cambridge-10.1017/S1047951100004959 Persistence of the left superior caval vein: can it potentiate obstructive lesions of the left ventricle? [Elektronische Daten] Recent evidence has suggested that persistence of the left superior caval vein is associated with a high incidence of obstructive lesions of the left heart. To shed more light on this issue 1085 patients with congenital heart disease were studied retrospectively, with the aim of estimating the prevalence of a persistent left superior caval vein and its associated anomalies, focusing attention on obstructive lesions in the left and right ventricles. Patients with isomerism of the atrial appendages, or hypoplastic left heart syndrome, were excluded. A persisting left superior caval vein was present in 57 patients (5.2%). The overall incidence of obstructive lesions of the left heart was higher in patients with than in those without a persistent left superior caval vein (31.6 versus 7.8%, p < 0.001). Relative hypoplasia of the left ventricle was also higher in patients with persistent left superior caval vein (14 versus 0.8%, p < 0.001). The obstructive lesions found in the left heart, compared with the number in those without a left caval vein, were: mitral stenosis, 5.2 versus 0.7%; subaortic stenosis, 5.3 versus 0.9%; aortic coarctation, 17.5 versus 5.8% (p < 0.01); all of these in association, 3.5 versus 0.4%. In contrast, the incidence of obstructive lesions of the right heart was similar in the two groups of patients. It is concluded that persistence of the left superior caval vein can perturb the normal development of the left ventricle, being strongly associated with obstructions to left ventricular inflow and outflow. Copyright © Cambridge University Press 1999 Coronary sinus nationallicence hypoplastic left ventricle nationallicence abnormal systemic venous connections nationallicence Agnoletti Gabriella Divisione di Cardiologia e Ospedali Riuniti, Bergamo, Italy Annecchino Francesco Cardiochirurgia, Ospedali Riuniti, Bergamo, Italy Preda Laura Divisione di Cardiologia e Ospedali Riuniti, Bergamo, Italy Borghi Adele Divisione di Cardiologia e Ospedali Riuniti, Bergamo, Italy Cardiology in the Young Cambridge University Press 9/3(1999-05), 285-290 1047-9511 9:3<285 1999 9 CTY https://doi.org/10.1017/S1047951100004959 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S1047951100004959 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Agnoletti Gabriella Divisione di Cardiologia e Ospedali Riuniti, Bergamo, Italy NATIONALLICENCE 700 1- Annecchino Francesco Cardiochirurgia, Ospedali Riuniti, Bergamo, Italy NATIONALLICENCE 700 1- Preda Laura Divisione di Cardiologia e Ospedali Riuniti, Bergamo, Italy NATIONALLICENCE 700 1- Borghi Adele Divisione di Cardiologia e Ospedali Riuniti, Bergamo, Italy NATIONALLICENCE 773 0- Cardiology in the Young Cambridge University Press 9/3(1999-05), 285-290 1047-9511 9:3<285 1999 9 CTY CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge