caa a22 4500 397494297 CHVBK 20180308164517.0 cr unu---uuuuu 161202e199512 xx s 000 0 eng 10.1093/oxfordjournals.jbchem.a125017 doi (NATIONALLICENCE)oxford-10.1093/oxfordjournals.jbchem.a125017 Tissue-Type Transglutaminase Is Not a Tumor-Related Marker [Elektronische Daten] [Kazuaki Takaku, Mayumi Futamura, Shio Saitoh, Yutaka Takeuchi] The level of transglutaminase (TGase) expressed in various tumor cell lines was investigated. We found that each cell line could be categorized into three distinct groups, that is, (i) cell lines with low or negligible TGase activity, (ii) cell lines with significant or high TGase activity and immunoreactive to a monoclonal antibody against tissue type TGase, and (iii) cell line with significant or high TGase activity but not immunoreactive to the antibody.Results reported here argue against the former proposal that tissue-type TGase is expressed at a lower level in malignant cells compared to the level in normal cells. © Oxford University Press Regular Papers nationallicence immunoblotting nationallicence transglutaminase nationallicence tumor cell nationallicence Takaku Kazuaki Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut Futamura Mayumi Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut Saitoh Shio Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut Takeuchi Yutaka Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut The Journal of Biochemistry Oxford University Press 118/6(1995-12), 1268-1270 0021-924X 118:6<1268 1995 118 jbchem https://doi.org/10.1093/oxfordjournals.jbchem.a125017 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/oxfordjournals.jbchem.a125017 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Takaku Kazuaki Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut NATIONALLICENCE 700 1- Futamura Mayumi Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut NATIONALLICENCE 700 1- Saitoh Shio Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut NATIONALLICENCE 700 1- Takeuchi Yutaka Banyu Tsukuba Research Institute in Collaboration with Merck Research Laboratory, 3 Okubo, Tsukuba, Ibaraki 300-33 aut NATIONALLICENCE 773 0- The Journal of Biochemistry Oxford University Press 118/6(1995-12), 1268-1270 0021-924X 118:6<1268 1995 118 jbchem Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford