caa a22 4500 397495323 CHVBK 20180308164519.0 cr unu---uuuuu 161202e199511 xx s 000 0 eng 10.1016/S1010-7940(05)80104-6 doi (NATIONALLICENCE)oxford-10.1016/S1010-7940(05)80104-6 Second primary lung cancer and relapse: treatment and follow-up [Elektronische Daten] During a 14-year period (1980-1993) second primary lung cancer orrelapse was treated in 44 consecutive patients. Thirty-seven patients hadsynchronous (n = 18) or metachronous (n = 19) second primary lung cancer.Ten synchronous tumors were ipsilateral and treated contemporarily withfive pneumonectomies, three lobectomies and two double wedge resections.The bilateral synchronous lesions (8 patients) were treated by stagedbilateral thoracotomy (mean interval; 2 months). The first resectionconsisted of a lobectomy in six patients and wedge resection in two. Thesecond one was a wedge resection in six patients and a lobectomy in two. Inthe metachronous presentation 15 patients (79%) were asymptomatic anddetected by follow-up chest X-ray. In this group the first operation was alobectomy in 12 patients, a wedge resection or segmentectomy in 6 and apneumonectomy in 1. The second one was a wedge resection in nine patients,a lobectomy in six and completion pneumonectomy in four. Seven patients,all of them asymptomatic, had local recurrence from their primary lungcancer. The first lung resection was a lobectomy in five patients and awedge resection in two. The second one was completion pneumonectomy in fivepatients and completion lobectomy in two. We had no operative death. Theactuarial over-all 5-year survival rate after the second pulmonaryresection for second primary lung cancer was 38.3% with a median survivaltime of 13.5 months. The synchronous presentation had a better survivalthan the metachronous one (46.2% and 25.9%), respectively). The actuarialoverall 5-year survival rate for patients with relapse was 38.1% with amedian survival time of 37 months. We may conclude that an aggressivesurgical approach is safe, effective and warranted in patients with eithera second primary lung cancer or relapse from their primary lung cancer.Moreover, for early detection of the second lesions, follow-up at a maximumof 6-monthly intervals should be continued for more than 5 years after thefirst resection. © Springer-Verlag European Journal of Cardio-Thoracic Surgery Elsevier Science B.V. 9/11(1995-11), 607-611 1010-7940 9:11<607 1995 9 ejcts https://doi.org/10.1016/S1010-7940(05)80104-6 text/html Onlinezugriff via DOI 1 abstract jats NATIONALLICENCE 856 40 https://doi.org/10.1016/S1010-7940(05)80104-6 text/html Onlinezugriff via DOI NATIONALLICENCE 773 0- European Journal of Cardio-Thoracic Surgery Elsevier Science B.V 9/11(1995-11), 607-611 1010-7940 9:11<607 1995 9 ejcts Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford