caa a22 4500 397495447 CHVBK 20180308164519.0 cr unu---uuuuu 161202e199505 xx s 000 0 eng 10.1016/S1010-7940(05)80159-9 doi (NATIONALLICENCE)oxford-10.1016/S1010-7940(05)80159-9 Mitral valve replacement with the Carpentier-Edwards standard bioprosthesis: performance into the second decade [Elektronische Daten] From March 1978, 196 Carpentier-Edwards standard bioprostheses (stCE)were implanted in 194 patients. There were 154 isolated mitral valvereplacements (MVR) and 42 aortic plus mitral valve replacements (AVR/MVR)with a mean follow-up of 7.05 (range 0-15.2) years and 7.15 (range 0-13.8)years, respectively. Freedom from structural valve failure at 10 years was70.8% +/- 4.9% (MVR) and 59.6% +/- 11.1% (AVR/MVR). The incidence ofstructural valve failure increased sharply after 7 years. Freedom fromthromboembolism was 83.0% +/- 3.8% (MVR) and 89.0 +/- 6.0% (AVR/MVR).Thromboembolic events were related to the presence of atrial fibrillationin patients not receiving anticoagulation. Anticoagulant-relatedhaemorrhage was rare. Freedom from mitral valve prosthetic endocarditis at10 years was 90.9% +/- 3.1% (MVR) and 86.1% +/- 8.4% (AVR/MVR). Prostheticvalve endocarditis was associated with more than 60% mortality. Theprobability of event- free survival at 10 years follow-up was 43.6% +/-4.6% (MVR) and 33.3% +/- 8.6% (AVR/MVR). The performance of the stCE in themitral position shows a low rate of thromboembolic events andanticoagulant-related haemorrhage, but the long-term performance of theprosthesis is unsatisfactory due to a high rate of structural valvefailure. This confirms earlier reports. European Journal of Cardio-Thoracic Surgery Elsevier Science B.V. 9/5(1995-05), 253-258 1010-7940 9:5<253 1995 9 ejcts https://doi.org/10.1016/S1010-7940(05)80159-9 text/html Onlinezugriff via DOI 1 abstract jats NATIONALLICENCE 856 40 https://doi.org/10.1016/S1010-7940(05)80159-9 text/html Onlinezugriff via DOI NATIONALLICENCE 773 0- European Journal of Cardio-Thoracic Surgery Elsevier Science B.V 9/5(1995-05), 253-258 1010-7940 9:5<253 1995 9 ejcts Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford