caa a22 4500 397495455 CHVBK 20180308164519.0 cr unu---uuuuu 161202e199505 xx s 000 0 eng 10.1016/S1010-7940(05)80160-5 doi (NATIONALLICENCE)oxford-10.1016/S1010-7940(05)80160-5 Randomised, prospective evaluation of a new pericardial heart valve: outcome after seven years [Elektronische Daten] Between 2 February 1987 and 20 March 1990, 170 patients were randomlyallocated to receive a new pericardial heart valve (the Bioflo) or theCarpentier-Edwards supra-annular porcine bioprosthesis. Eighty-fivepatients (mean age 61 years, range 38-77) received 93 Bioflo valves, 46having aortic valve replacement (AVR), 31 mitral valve replacement (MVR)and 8 aortic and mitral valve replacement (A+MVR); 85 patients (mean age62.1 years, range 41-77) received 99 Carpentier-Edwards porcine valves (48AVR, 23 MVR and 14 A+MVR). Cumulative follow-up totals 926 patient-years(mean 5.45 +/- 1.93, median 6.03, maximum 7.47 years). The overalloperative mortality rate for the Bioflo group was 2.4%, and 5.9% for theCarpentier-Edwards group. At 7 years, there was no statisticallysignificant difference in survival or in any prosthesis-relatedcomplication between the pericardial and porcine valve recipients overall,or when the data were analysed according to valve implant position. Theactuarial survival rate at 7 years for the Bioflo group was 80.1 +/- 5.1%and 72.3 +/- 5.9% for the Carpentier- Edwards group. Freedom fromstructural valve deterioration (SVD) at 7 years for Bioflo patients was98.5 +/- 1.5% and for Carpentier-Edwards patients 91.2 +/- 4.1%. No patientin the Bioflo group has required reoperation for SVD. The randomisedprospective trial has proven practical and effective and has shown thepericardial valve to perform at least as well as the porcine valve up to 7years when all of the standard outcome measures of valve performance areassessed. European Journal of Cardio-Thoracic Surgery Elsevier Science B.V. 9/5(1995-05), 259-267 1010-7940 9:5<259 1995 9 ejcts https://doi.org/10.1016/S1010-7940(05)80160-5 text/html Onlinezugriff via DOI 1 abstract jats NATIONALLICENCE 856 40 https://doi.org/10.1016/S1010-7940(05)80160-5 text/html Onlinezugriff via DOI NATIONALLICENCE 773 0- European Journal of Cardio-Thoracic Surgery Elsevier Science B.V 9/5(1995-05), 259-267 1010-7940 9:5<259 1995 9 ejcts Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford