caa a22 4500 397495862 CHVBK 20180308164520.0 cr unu---uuuuu 161202e199507 xx s 000 0 eng 10.1016/S1010-7940(05)80166-6 doi (NATIONALLICENCE)oxford-10.1016/S1010-7940(05)80166-6 Results of pneumonectomy for cancer in patients with limited ventilatory function [Elektronische Daten] It is well established that patients with compromised pulmonary functionhave a greater incidence of morbidity and mortality following lungresection. The prognosis of 36 (9.7%) patients with poor respiratoryfunction (forced expiratory volume in ls (FEV1) and FEV1/FVC (forced vitalcapacity) ratio were equal to or less than 50% of the predicted value) of atotal of 369 patients who underwent pneumonectomy due to non-small celllung carcinoma over 10 years were reviewed. All but three patients weremale with a median age of 62.5 years. Right pneumonectomy was carried outin 12 (33%) and left in 24 (67%) patients. Median FEV1 and FEV1/FVC were1.51 (46%) and 46.5% respectively. Three (8%) patients died within 30 daysof surgery. The postoperative complication rate in patients with poorrespiratory function was 44%. Nine (27%) of the hospital survivors died dueto non- malignant causes (recurrent chest infection/respiratory failure)and 12 (36%) due to recurrent tumour. The cause of death in one patient wassecond primary lung tumour and it was unknown in three (9%) patients. Eight(24%) long-term surviving patients did not have severe respiratorysymptoms; their FEV1 and FEV1/FVC were remeasured and revealed a median1.05 l (38%) and 50%, respectively of the predicted value. Actuarial 5-yearsurvival was 29%. Poor respiratory function is associated withpostoperative complications and non-malignant deaths arising secondary torespiratory failure. The survival profile demonstrates that patients weresuccessfully treated with pneumonectomy and suggests that surgery shouldnot be withheld from those with limited lung function if detailedinvestigations predict adequate residual lung function. European Journal of Cardio-Thoracic Surgery Elsevier Science B.V. 9/7(1995-07), 347-351 1010-7940 9:7<347 1995 9 ejcts https://doi.org/10.1016/S1010-7940(05)80166-6 text/html Onlinezugriff via DOI 1 abstract jats NATIONALLICENCE 856 40 https://doi.org/10.1016/S1010-7940(05)80166-6 text/html Onlinezugriff via DOI NATIONALLICENCE 773 0- European Journal of Cardio-Thoracic Surgery Elsevier Science B.V 9/7(1995-07), 347-351 1010-7940 9:7<347 1995 9 ejcts Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford