caa a22 4500 397495870 CHVBK 20180308164520.0 cr unu---uuuuu 161202e199507 xx s 000 0 eng 10.1016/S1010-7940(05)80172-1 doi (NATIONALLICENCE)oxford-10.1016/S1010-7940(05)80172-1 Reactive thrombocytosis after coronary bypass surgery. An important risk factor [Elektronische Daten] Reactive thrombocytosis (RT) has earlier been reported to occur as aresponse to various situations and conditions, such as post- splenectomy,hematopoietic disorders, major trauma and operations, neoplasms andinflammations. In cardiac surgery the main interest has focused onthrombocytopenia that occurs after cardiopulmonary bypass (CPB) and therisk of postoperative bleeding, rather than the possibility of a lateoccurrence of RT as a risk factor for thrombotic complications aftercoronary artery bypass grafting (CABG). Between 1989 and 1992, on routineblood examinations we noticed a group of CABG patients (n = 297, Group II,19.5%) that, 1 week after operation, showed thrombocytosis withsignificantly increased platelet count (521 +/- 96 x 10(3)/mm3) compared topatients with normal platelet counts (Group I, n = 1521, 185 +/- 125 x10(3)/mm3); P < 0.001. Patient characteristics, coronary angiographyfindings, operative data and perioperative complications were analyzed forthe two groups. There were significantly more patients with hyperlipidemia,smoking and previous myocardial infarction in Group II than in Group I; P< 0.05. Age, sex, clinical characteristics, angiography findings andoperative data did not differ between the groups. There were no differencesin postoperative bleeding or the need of transfusion between the groups.However, Group II (RT) patients had significantly more postoperativemyocardial infarctions, 4.4% compared to 0.7% Group I; P < 0.001. Earlysymptomatic vein graft occlusion (0-7 days postoperatively) was notdifferent between the groups, while there were significantly move latesymptomatic vein graft occlusions (7-60 days postoperatively) in Group II(RT) 4.4% than in Group I 1.1%; P < 0.001.(ABSTRACT TRUNCATED AT 250WORDS) European Journal of Cardio-Thoracic Surgery Elsevier Science B.V. 9/7(1995-07), 393-397 1010-7940 9:7<393 1995 9 ejcts https://doi.org/10.1016/S1010-7940(05)80172-1 text/html Onlinezugriff via DOI 1 abstract jats NATIONALLICENCE 856 40 https://doi.org/10.1016/S1010-7940(05)80172-1 text/html Onlinezugriff via DOI NATIONALLICENCE 773 0- European Journal of Cardio-Thoracic Surgery Elsevier Science B.V 9/7(1995-07), 393-397 1010-7940 9:7<393 1995 9 ejcts Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford