caa a22 4500 397496869 CHVBK 20180308164523.0 cr unu---uuuuu 161202e199509 xx s 000 0 eng 10.1016/S1010-7940(95)80053-0 doi (NATIONALLICENCE)oxford-10.1016/S1010-7940(95)80053-0 Mid-term results of heart transplantation for end-stage valvular disease [Elektronische Daten] The results of heart transplantation in a consecutive series of 19 end-stage valvular disease patients (15 male, aged 48 +/- 8 years) wereanalysed retrospectively. The indication for heart transplantation washeart failure due to left and/or right ventricular dysfunction; 16 patientshad undergone previous valve surgery, but prosthetic dysfunction waspresent in only one patient. All patients were in NYHA class IV, 15 were onoral anticoagulants and 5 on i.v. catecholamine support. There were fourin-hospital deaths (21%) and one late death (5%), resulting in a 1-yearmortality rate slightly, but not significantly, higher than that ofpatients transplanted for other indications (16%). Mean follow-up of thesurvivors was 48 +/- 33 months (range 9-95); 5-year actuarial survival wassimilar to that observed among the other heart transplantation patients (74+/- 10% vs 77 +/- 3%, P = NS). The incidence of acute rejection andinfection was also similar in valvular disease and non-valvular diseasepatients. Kidney and liver function at 1 year post-heart transplantationwas preserved in all cases; cardiac catheterization revealed normal graftfunction in all patients and the absence of coronary lesions in all buttwo. In conclusion, in our limited experience morbidity and mortality inpatients transplanted for end-stage valvular disease seem to be similar tothose of patients undergoing heart transplantation for otheretiologies. European Journal of Cardio-Thoracic Surgery Elsevier Science B.V. 9/9(1995-09), 521-525 1010-7940 9:9<521 1995 9 ejcts https://doi.org/10.1016/S1010-7940(95)80053-0 text/html Onlinezugriff via DOI 1 abstract jats NATIONALLICENCE 856 40 https://doi.org/10.1016/S1010-7940(95)80053-0 text/html Onlinezugriff via DOI NATIONALLICENCE 773 0- European Journal of Cardio-Thoracic Surgery Elsevier Science B.V 9/9(1995-09), 521-525 1010-7940 9:9<521 1995 9 ejcts Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford