caa a22 4500 397496915 CHVBK 20180308164523.0 cr unu---uuuuu 161202e199509 xx s 000 0 eng 10.1016/S1010-7940(95)80050-6 doi (NATIONALLICENCE)oxford-10.1016/S1010-7940(95)80050-6 Cryopreserved arterial homografts for in situ reconstruction of mycotic aneurysms and prosthetic graft infection [Elektronische Daten] The management of mycotic aneurysms and prosthetic graft infection ofmajor thoracic and abdominal vessels and infected extra-anatomic bypassremains a problem in vascular surgery. Cryopreserved arterial homografts,being resistant to infection, offer hope for in situ vascularreconstruction in the presence of an infection. We analyzed clinical,microbiological, preoperative and postoperative magnetic resonance imaging(MRI), computed tomography (CT), echocardiography and/or angiography datain 12 patients with mycotic aneurysm or prosthetic graft infection, in whomcryopreserved arterial homografts were used to replace infected segments ofmajor thoracic and abdominal vessels. The hospital mortality was 8.3%. Theaverage postoperative hospital stay was 18 +/- 14.5 days (6 to 45);antibiotic treatment was continued for 31 +/- 12 days (4 to 42). During themean follow-up time of 18.6 +/- 12.8 months (2 to 48) two patients died,but only one (9%) was homograft-related. Recurrence of infection, sutureline problems or homograft stenosis or aneurysm were not observed.Therefore, in situ replacement with cryopreserved arterial homografts is aneffective treatment for mycotic aneurysms and graft infection of thoracicaorta, abdominal aortic/iliac vessels and infected extra-anatomic bypass.This operative technique has a low early and late mortality, obviates theneed for complex extra-anatomic reconstruction, allows safe in situ repair,reduces postoperative antibiotic requirements, shortens the hospital stayand renders early or medium-term reoperations unnecessary. European Journal of Cardio-Thoracic Surgery Elsevier Science B.V. 9/9(1995-09), 502-506 1010-7940 9:9<502 1995 9 ejcts https://doi.org/10.1016/S1010-7940(95)80050-6 text/html Onlinezugriff via DOI 1 abstract jats NATIONALLICENCE 856 40 https://doi.org/10.1016/S1010-7940(95)80050-6 text/html Onlinezugriff via DOI NATIONALLICENCE 773 0- European Journal of Cardio-Thoracic Surgery Elsevier Science B.V 9/9(1995-09), 502-506 1010-7940 9:9<502 1995 9 ejcts Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford