caa a22 4500 397502656 CHVBK 20180308164536.0 cr unu---uuuuu 161202e19951001xx s 000 0 eng 10.1093/oxfordjournals.rpd.a082815 doi 0144-8420 pii (NATIONALLICENCE)oxford-10.1093/oxfordjournals.rpd.a082815 Late Effects of Low Level Irradiation [Elektronische Daten] [I.I. Pelevina, V.Ja. Gotlib, G.G. Afanasjev] The effect of low level irradiation may be delayed for many generations in HeLa cells. When the progeny of irradiated cells was seeded 15-30 generations after irradiation (0.1-0.5 Gy 60Co ? rays, 0.3 Gy.min-1; or in the Chernobyl zone 0.1-0.5 Gy, 0.003-0.005 Gy.h-1) they formed clones with a reduced number of cells. There are giant cells and cells with micronuclei in such clones. Progeny of surviving HeLa cells showed a reduced cloning efficiency and enhanced radiosensitivity. These results suggest that residual damage may by carried by surviving progeny over many generations and expressed as changes which lead to delayed reproductive death. Radiation Protection Dosimetry Pelevina I.I. aut Gotlib V.Ja aut Afanasjev G.G. aut Radiation Protection Dosimetry Oxford University Press 62/1-2(1995-10-01), 35-36 0144-8420 62:1-2<35 1995 62 rpd https://doi.org/10.1093/oxfordjournals.rpd.a082815 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/oxfordjournals.rpd.a082815 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pelevina I.I. aut NATIONALLICENCE 700 1- Gotlib V.Ja aut NATIONALLICENCE 700 1- Afanasjev G.G. aut NATIONALLICENCE 773 0- Radiation Protection Dosimetry Oxford University Press 62/1-2(1995-10-01), 35-36 0144-8420 62:1-2<35 1995 62 rpd Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford