caa a22 4500 397504497 CHVBK 20180308164541.0 cr unu---uuuuu 161202e19950701xx s 000 0 eng 10.1093/oxfordjournals.rpd.a082740 doi 0144-8420 pii (NATIONALLICENCE)oxford-10.1093/oxfordjournals.rpd.a082740 Kathren (INVITED) R.L. INVITED The United States Transuranium and Uranium Registries: 1968-1993 [Elektronische Daten] [R.L. Kathren (INVITED)] The historical development and scientific contributions of the United States Transuranium and Uranium Registries are briefly traced. Further to encourage radiobiology studies and to provide unique materials for research in other areas such as biomarkers including oncogenes, the Registries have established the National Human Radiobiology Tissue Repository, which includes more than 20,000 tissue samples solutions, histopathology slides, and related materials from persons with internal deposition, including radium dial painters, available to other investigators for collaborative or individual research purposes. Emphasis is given to recent findings of the Registries with respect to biokinetic models for the actinides and the post-mortem analysis of USTUR Case 0246, an individual who suffered a massive intake of 241Am eleven years prior to death from heart disease. Registries studies show that, in addition to skeleton and liver, muscle is an appreciable reservoir for both plutonium and americium. The systemic biokinetics of plutonium and americium are well represented by a three-compartment model that includes skeleton, liver, and muscle, although the biokinetic parameters of these two transuranium elements differ significantly. Initial uptake fractions for plutonium are 0.4, 0.4, and 0.2, with residence half-times of 50, 20 and 10 years, respectively, for skeleton, liver and muscle. For americium, the comparable uptake fractions are 0.45, 0.25, 0.3 with residence half-times of 50, 2.5 and 10 years for the three compartments. Radiation Protection Dosimetry Radiation Protection Dosimetry Oxford University Press 60/4(1995-07-01), 349-354 0144-8420 60:4<349 1995 60 rpd https://doi.org/10.1093/oxfordjournals.rpd.a082740 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/oxfordjournals.rpd.a082740 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Kathren (INVITED) R.L. INVITED NATIONALLICENCE 773 0- Radiation Protection Dosimetry Oxford University Press 60/4(1995-07-01), 349-354 0144-8420 60:4<349 1995 60 rpd Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence SWISSBIB 396153461 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford