caa a22 4500 39750473X CHVBK 20180308164541.0 cr unu---uuuuu 161202e19951001xx s 000 0 eng 10.1093/oxfordjournals.rpd.a082824 doi 0144-8420 pii (NATIONALLICENCE)oxford-10.1093/oxfordjournals.rpd.a082824 Frequency Changes of Inherited Anomalies in the Republic of Belarus After the Chernobyl Accident [Elektronische Daten] [G.I. Lazjuk, I.A. Kirillova, D.L. Nikolaev, I.V. Novikova, Z.N. Formina, R.D. Khmel] Complex cytogenetic, embryologic and clinical studies of possible genetic consequences of the Chernobyl nuclear accident for the population of Belarus have been carried out. They showed that groups of the population (pregnant women, fetuses, school children) had received biologically significant doses of radiation, as assessed by the registration of ring and dicentric chromosomes in blood lymphocytes. The study of more than 22,000 embryos and fetuses, and of 4090 neonates with compulsory registered congenital malformations, showed a considerable increase of anomalies of intrauterine origin since 1987. They correlated with the level of 137Cs contamination in the areas, but did not correlate with the preconception dose to the mother from the same radionuclide. Teratogenic effects of the Chernobyl pollution have not been conclusively identified. The increase of embryonal anomalies was mainly due to the group of multifactorial defects, and to the anomalies with a large contribution from dominant mutations. The Down's Syndrome incidence showed no increase. Radiation Protection Dosimetry Lazjuk G.I. aut Kirillova I.A. aut Nikolaev D.L. aut Novikova I.V. aut Formina Z.N. aut Khmel R.D. aut Radiation Protection Dosimetry Oxford University Press 62/1-2(1995-10-01), 71-74 0144-8420 62:1-2<71 1995 62 rpd https://doi.org/10.1093/oxfordjournals.rpd.a082824 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/oxfordjournals.rpd.a082824 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lazjuk G.I. aut NATIONALLICENCE 700 1- Kirillova I.A. aut NATIONALLICENCE 700 1- Nikolaev D.L. aut NATIONALLICENCE 700 1- Novikova I.V. aut NATIONALLICENCE 700 1- Formina Z.N. aut NATIONALLICENCE 700 1- Khmel R.D. aut NATIONALLICENCE 773 0- Radiation Protection Dosimetry Oxford University Press 62/1-2(1995-10-01), 71-74 0144-8420 62:1-2<71 1995 62 rpd Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford