caa a22 4500 397520298 CHVBK 20180308164630.0 cr unu---uuuuu 161202e199512 xx s 000 0 eng 10.1093/heapol/10.4.404 doi (NATIONALLICENCE)oxford-10.1093/heapol/10.4.404 Knowledge, attitudes and practices during a community-level ivermectin distribution campaign in Guatemala [Elektronische Daten] [FRANK O RICHARDS, ROBERT E KLEIN, CARLOS GONZÁLES-PERALTA, RODOLFO ZEA FLORES, SHEILA GONGORA ROMAN, JULIO CASTRO RAMÍREZ, GUILLERMO ZEA FLORES] Community acceptance and participation are essential for the success of mass ivermectin chemotherapy programmes for onchocerciasis (river blindness). To explore the local understanding of the purpose of ivermectin and willingness to continue taking the drug, we performed questionnaire surveys in four communities with hyperendemic onchocerciasis after each of three ivermectin treatment rounds. More than 100 respondents participated in each KAP survey, representing the heads of 30% of the households in each community. The respondents rarely stated that the goal of the ivermectin treatment programme was to prevent visual loss. Instead, they said they were taking the drug for their general well-being, to cure the onchocercal nodule (filaria), or to cure the microfilaria, a term newly introduced by agents of the treatment programme. The principal reason identified for refusal to take ivermectin was anxiety about drug-related adverse reactions, and there were marked differences between communities in acceptance of treatment. In one community over 50% of residents initially refused to take ivermectin, although participation rates improved somewhat after programmatic adjustments. We recommend that ivermectin distribution programmes establish surveillance activities to detect where acceptance is poor, so that timely and community-specific adjustments may be devised to improve participation. © Oxford University Press Review paper nationallicence RICHARDS FRANK O. Division of Parasitic Diseases, Centers for Disease Control and Prevention Atlanta, USA aut KLEIN ROBERT E. Medical Entomology Research and Training Unit, Centers for Disease Control and Prevention Atlanta, USA aut GONZÁLES-PERALTA CARLOS River Blindness Foundation Texas, USA aut FLORES RODOLFO ZEA Medical Entomology Research and Training Unit, Centers for Disease Control and Prevention Atlanta, USA aut ROMAN SHEILA GONGORA Medical Entomology Research and Training Unit, Centers for Disease Control and Prevention Atlanta, USA aut RAMÍREZ JULIO CASTRO Departamento de Oncocercosis, Ministerio de Salud Pública y Asistencia Social Guatemala aut FLORES GUILLERMO ZEA Onchocerciasis Elimination Program of the Americas (OEPA) Antigua, Guatemala aut Health Policy and Planning Oxford University Press 10/4(1995-12), 404-414 0268-1080 10:4<404 1995 10 heapol https://doi.org/10.1093/heapol/10.4.404 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/heapol/10.4.404 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- RICHARDS FRANK O. Division of Parasitic Diseases, Centers for Disease Control and Prevention Atlanta, USA aut NATIONALLICENCE 700 1- KLEIN ROBERT E. Medical Entomology Research and Training Unit, Centers for Disease Control and Prevention Atlanta, USA aut NATIONALLICENCE 700 1- GONZÁLES-PERALTA CARLOS River Blindness Foundation Texas, USA aut NATIONALLICENCE 700 1- FLORES RODOLFO ZEA Medical Entomology Research and Training Unit, Centers for Disease Control and Prevention Atlanta, USA aut NATIONALLICENCE 700 1- ROMAN SHEILA GONGORA Medical Entomology Research and Training Unit, Centers for Disease Control and Prevention Atlanta, USA aut NATIONALLICENCE 700 1- RAMÍREZ JULIO CASTRO Departamento de Oncocercosis, Ministerio de Salud Pública y Asistencia Social Guatemala aut NATIONALLICENCE 700 1- FLORES GUILLERMO ZEA Onchocerciasis Elimination Program of the Americas (OEPA) Antigua, Guatemala aut NATIONALLICENCE 773 0- Health Policy and Planning Oxford University Press 10/4(1995-12), 404-414 0268-1080 10:4<404 1995 10 heapol Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford