caa a22 4500 397542836 CHVBK 20180308164731.0 cr unu---uuuuu 161202s1995 xx s 000 0 eng 10.1093/japr/4.3.271 doi (NATIONALLICENCE)oxford-10.1093/japr/4.3.271 Possible Toxic Effects of Gentamicin in Newly Hatched Turkey Poults [Elektronische Daten] [W. E. Donaldson, V. L. Christensen] When poults hatch, they have limited carbohydrate reserves. Hatchery servicing (cloacal sexing, desnooding, beak and toe trimming, and injections) depletes those reserves and places the poults at increased risk of early mortality. Hatchery injections frequently include gentamicin to control bacterial infections in newly hatched turkey poults. In the experiments reported here, gentamicin injections decreased the activities of glucose-6-phosphatase (G-6-Pase) and phosphoenolpyruvate carboxykinase (PEPCK) - both gluconeogenic enzymes - and increased muscle lactate concentration. Both results are consistent with lowered gluconeogenic capacity. The increased concentration of plasma uric acid and the reduced clearance of phenol red from the blood in gentamicin-injected poults are indications of impaired kidney function. The results suggest that the use of gentamicin injections (1 mg/poult) in newly hatched turkeys may be detrimental and could be a risk factor for early poult mortality. © 1995 Applied Poultry Science, Inc. Antibiotic injection nationallicence early poult mortality nationallicence gentamicin nationallicence nephrotoxicity nationallicence Donaldson W. E. Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608; Phone: (919) 515-2626; FAX: (919) 515-2625 aut Christensen V. L. Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608; Phone: (919) 515-2626; FAX: (919) 515-2625 aut Journal of Applied Poultry Research Oxford University Press 4/3(1995), 271-275 1056-6171 4:3<271 1995 4 japr https://doi.org/10.1093/japr/4.3.271 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/japr/4.3.271 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Donaldson W. E. Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608; Phone: (919) 515-2626; FAX: (919) 515-2625 aut NATIONALLICENCE 700 1- Christensen V. L. Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608; Phone: (919) 515-2626; FAX: (919) 515-2625 aut NATIONALLICENCE 773 0- Journal of Applied Poultry Research Oxford University Press 4/3(1995), 271-275 1056-6171 4:3<271 1995 4 japr Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford