caa a22 4500 397542925 CHVBK 20180308164731.0 cr unu---uuuuu 161202s1995 xx s 000 0 eng 10.1093/japr/4.4.333 doi (NATIONALLICENCE)oxford-10.1093/japr/4.4.333 Craven Stephen E. USDA, ARS, Russell Agricultural Research Center, P. O. Box 5677, Athens, GA 30604; Phone: (706) 546-3986; FAX: (706) 546-3771 Salmonella typhimurium, Hydrophobic Antibiotics, and the Intestinal Colonization of Broiler Chicks [Elektronische Daten] [Stephen E. Craven] In vitro, Salmonella typhimurium is resistant to concentrations of hydrophobic antibiotics (novobiocin, rifampicin, spectinomycin, trimethoprim) which inhibit other bacteria. Some of these antibiotics are used in poultry production. Membrane-disorganizing agents, both metal chelators and polycations, decreased the concentration of trimethoprim that inhibited the growth of S. typhimurium in vitro. Administration of novobiocin, rifampicin, and spectinomycin to the drinking water of young chicks significantly increased cecal colonization of an experimental strain of S. typhimurium. However, trimethoprim significantly reduced number of S. typhimurium in the ceca, even though this organism was resistant to trimethoprim in vitro. © 1995 Applied Poultry Science, Inc. Broilers nationallicence hydrophobic antibiotics nationallicence intestinal colonization nationallicence outer membrane nationallicence Salmonella typhimurium nationallicence Journal of Applied Poultry Research Oxford University Press 4/4(1995), 333-340 1056-6171 4:4<333 1995 4 japr https://doi.org/10.1093/japr/4.4.333 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/japr/4.4.333 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Craven Stephen E. USDA, ARS, Russell Agricultural Research Center, P. O. Box 5677, Athens, GA 30604; Phone: (706) 546-3986; FAX: (706) 546-3771 NATIONALLICENCE 773 0- Journal of Applied Poultry Research Oxford University Press 4/4(1995), 333-340 1056-6171 4:4<333 1995 4 japr Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford