caa a22 4500 397556659 CHVBK 20180308164804.0 cr unu---uuuuu 161202e199608 xx s 000 0 eng 10.1093/oxfordjournals.jbchem.a021403 doi (NATIONALLICENCE)oxford-10.1093/oxfordjournals.jbchem.a021403 Real Time Observation of the Binding of Herpes Simplex Virus Type 1 (HSV-1) to Immobilized Heparan Sulfate and the Neutralization of HSV-1 by Sulfonated Human Immunoglobulin [Elektronische Daten] [Kazuko Inoue, Toshihiko Arai, Masaaki Aoyagi] A real time biomolecular interaction assay system involving an optical sensor was applied to quantitative analysis of the binding of herpes simplex virus type 1 (HSV-1) to immobilized heparan sulfate, a cellular receptor component of HSV-1, and the neutralization antibody titer against this virus with a commercially available sulfonated human immunoglobulin preparation. The virus titer in a viral solution and the neutralizing antibody titer in the human immunoglobulin preparation could be successfully estimated in a short time with this system without any difficult cell culture. © 1996 BY THE JOURNAL OF BIOCHEMISTRY Rapid Communications nationallicence herpes simplex virus type 1 nationallicence human immunoglobulin nationallicence molecular interaction nationallicence optical biosensor nationallicence Inoue Kazuko Department of Microbiology, Meiji College of Pharmacy 1-35-23 Nozawa, Setagaya-ku, Tokyo 154 aut Arai Toshihiko Department of Microbiology, Meiji College of Pharmacy 1-35-23 Nozawa, Setagaya-ku, Tokyo 154 aut Aoyagi Masaaki Scientific Instruments Laboratory, Nissei Sangyo Co., Ltd. Atsugi, Tokyo 243-01 aut The Journal of Biochemistry Oxford University Press 120/2(1996-08), 233-235 0021-924X 120:2<233 1996 120 jbchem https://doi.org/10.1093/oxfordjournals.jbchem.a021403 text/html Onlinezugriff via DOI 1 other jats NATIONALLICENCE 856 40 https://doi.org/10.1093/oxfordjournals.jbchem.a021403 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Inoue Kazuko Department of Microbiology, Meiji College of Pharmacy 1-35-23 Nozawa, Setagaya-ku, Tokyo 154 aut NATIONALLICENCE 700 1- Arai Toshihiko Department of Microbiology, Meiji College of Pharmacy 1-35-23 Nozawa, Setagaya-ku, Tokyo 154 aut NATIONALLICENCE 700 1- Aoyagi Masaaki Scientific Instruments Laboratory, Nissei Sangyo Co., Ltd. Atsugi, Tokyo 243-01 aut NATIONALLICENCE 773 0- The Journal of Biochemistry Oxford University Press 120/2(1996-08), 233-235 0021-924X 120:2<233 1996 120 jbchem Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford