caa a22 4500 397557558 CHVBK 20180308164807.0 cr unu---uuuuu 161202e199604 xx s 000 0 eng 10.1093/oxfordjournals.jbchem.a021310 doi (NATIONALLICENCE)oxford-10.1093/oxfordjournals.jbchem.a021310 Androgenic Control of l-Alkyl-2,3-Diacylglycerol in the Harderian Gland of the Golden Hamster, Mesocricetus auratus [Elektronische Daten] [Yousuke Seyama, Azumi Hida, Shuichiro Hayashi, Gerald R. Buzzell] Harderian glands of golden hamsters produce a copious lipid secretion, most of which is in the form of l-alkyl-2,3-diacylglycerol (ADG). Sexual differences are seen in the composition of golden hamster ADG and in the morphology of secretory lipid droplet. ADGs from females contained abundant iso- and anteiso-branched chain alkyl groups and fatty acids [Seyama, Y., Otsuka, H., Ohashi, K., Vivien-Roels, B., and Pevet, P. (1995) J. Biochem, 117, 661-670]. Female hamsters were either untreated or given subcutaneous testosterone pellets. Treatment of females with testosterone led to the disappearance of such branched chain alkyl groups and fatty acids. Intact males had ADGs with entirely saturated straight chain alkyl groups and fatty acids. Castration led to the appearance of iso- and anteiso-branched chain alkyl groups and fatty acids. These observations suggested that the production of branched chain fatty acids in the Harderian gland of golden hamster is inhibited by testosterone at the step of isovaleryl-CoA dehydrogenase and 2-methyl branched-chain acyl-CoA dehydrogenase. © by the Journal of Biochemistry Regular Papers nationallicence acyl-CoA dehydrogenase nationallicence alkyldiacylglycerol nationallicence androgen nationallicence golden hamster nationallicence Harderian gland nationallicence Seyama Yousuke Department of Physiological Chemistry and Nutrition, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 aut Hida Azumi Department of Physiological Chemistry and Nutrition, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 aut Hayashi Shuichiro Department of Physiological Chemistry and Nutrition, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 aut Buzzell Gerald R. Department of Anatomy and Cell Biology, University of Alberta Edmonton, Alberta T6G 2H7, Canada aut The Journal of Biochemistry Oxford University Press 119/4(1996-04), 799-804 0021-924X 119:4<799 1996 119 jbchem https://doi.org/10.1093/oxfordjournals.jbchem.a021310 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/oxfordjournals.jbchem.a021310 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Seyama Yousuke Department of Physiological Chemistry and Nutrition, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 aut NATIONALLICENCE 700 1- Hida Azumi Department of Physiological Chemistry and Nutrition, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 aut NATIONALLICENCE 700 1- Hayashi Shuichiro Department of Physiological Chemistry and Nutrition, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 aut NATIONALLICENCE 700 1- Buzzell Gerald R. Department of Anatomy and Cell Biology, University of Alberta Edmonton, Alberta T6G 2H7, Canada aut NATIONALLICENCE 773 0- The Journal of Biochemistry Oxford University Press 119/4(1996-04), 799-804 0021-924X 119:4<799 1996 119 jbchem Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford