caa a22 4500 397567553 CHVBK 20180308164832.0 cr unu---uuuuu 161202e199612 xx s 000 0 eng 10.3382/ps.0751472 doi (NATIONALLICENCE)oxford-10.3382/ps.0751472 Effects of Feeding Fusarium moniliforme Culture Material, Containing Known Levels of Fumonisin B1, in the Young Turkey Poult [Elektronische Daten] [D. R. LEDOUX, A. J. BERMUDEZ, G. E. ROTTINGHAUS] The effects of feeding Fusarium moniliforme culture material, containing known concentrations of fumonisin B1 (FB1), were studied in turkey poults. Day-old poults were allotted randomly to dietary treatments containing 0, 0.41, 0.82, 1.23, 1.64, 2.87, 4.10, 5.33, 6.56, and 7.79% fumonisin culture material (FCM). These levels of FCM supplied 0, 25, 50, 75, 100, 175, 250, 325, 400, and 475 mg FB1/kg of feed. Each dietary treatment was fed to six pen replicates of six poults each for 21 d. Poults fed FCM that supplied 325 to 475 mg FB1/kg diet had lower (P < 0.05) feed intakes and BW gains. Increased (P < 0.05) liver and pancreas weights were observed in poults fed FCM that supplied ≥ 175 mg FB1/kg. Poults fed FCM that supplied 400 and 475 mg FB1/kg diet had increased (P < 0.05) red blood cell counts and increased (P < 0.05) serum concentrations of gamma glutamyl transferase and aspartate aminotransferase. Compared with controls, poults fed FCM that supplied 25, and 75 to 475 mg FB1/kg had increased (P < 0.05) liver sphinganine:sphingosine ratios. Hepatocellular hyperplasia was mild at 75 and 100 mg FB1/kg diet, moderate to severe at 250 mg/kg FB1, and severe at 325 to 475 mg FB1/kg. Multifocal to generalized loss of cross striations and thinning of cardiomyocytes was observed in poults fed FCM that supplied 475 mg FB1/kg diet. Results indicated that diets containing ≥ 1.23% FCM that supplied ≥ 75 mg FB1/kg are toxic to young turkeys. © 1996 Poultry Science Association, Inc. Environment and Health nationallicence fumonisin B1 nationallicence turkey nationallicence Fusarium moniliforme nationallicence sphinganine nationallicence sphingosine nationallicence LEDOUX D. R. 3To whom correspondence should be addressed: 112 Animal Sciences Center, Columbia, MO 65211. aut BERMUDEZ A. J. aut ROTTINGHAUS G. E. aut Poultry Science Oxford University Press 75/12(1996-12), 1472-1478 0032-5791 75:12<1472 1996 75 ps https://doi.org/10.3382/ps.0751472 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.3382/ps.0751472 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- LEDOUX D. R. 3To whom correspondence should be addressed: 112 Animal Sciences Center, Columbia, MO 65211 aut NATIONALLICENCE 700 1- BERMUDEZ A. J. aut NATIONALLICENCE 700 1- ROTTINGHAUS G. E. aut NATIONALLICENCE 773 0- Poultry Science Oxford University Press 75/12(1996-12), 1472-1478 0032-5791 75:12<1472 1996 75 ps Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford