caa a22 4500 397568169 CHVBK 20180308164833.0 cr unu---uuuuu 161202e199611 xx s 000 0 eng 10.3382/ps.0751428 doi (NATIONALLICENCE)oxford-10.3382/ps.0751428 Continuous Infusion of Adrenocorticotropin Elevates Circulating Lipoprotein Cholesterol and Corticosterone Concentrations in Chickens [Elektronische Daten] [MICKEY A. LATOUR, S. A. LAICHE, J. R. THOMPSON, A. L. POND, E. DAVID PEEBLES] The purpose of the present study was to investigate the effects of elevated corticosterone (CORT) on circulating lipoprotein cholesterol during a 1-wk period. For this study, 15 commercial broilers were randomly assigned to one of three treatment groups. Group 1 served as the control (CON) and received no treatment, whereas Groups 2 and 3 received subcutaneous mini-osmotic pumps containing either physiological saline (PS) or adrenocorticotropin (ACTH), respectively. The ACTH was delivered at a rate of 8 IU/kg of BW/d. Blood samples were taken at Time 0 (before implants) and on Days 2, 4, and 7 postimplantation. Continuous infusion of ACTH increased plasma glucose, cholesterol, triglycerides, very low density lipoprotein cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, and CORT during the postimplantation period. The group treated with ACTH also exhibited a decrease in BW during the last 2 sampling d. There were no differences in any of the serum constituents measured between CON and PS birds, which suggest that CON birds can serve as useful controls. These data suggest that birds given a continuous infusion of ACTH at 8 IU/kg of BW/d can experience changes in plasma lipoprotein cholesterol concentrations along with changes in other blood parameters and may serve as a useful model in accelerated lipoprotein production. © 1996 Poultry Science Association, Inc. Physiology and Reproduction nationallicence chicken nationallicence cholesterol nationallicence corticosterone nationallicence serum lipoprotein cholesterol nationallicence LATOUR MICKEY A. 3To whom correspondence should be addressed. aut LAICHE S. A. College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi 39762 aut THOMPSON J. R. Poultry Science Department and aut POND A. L. College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi 39762 aut PEEBLES E. DAVID Poultry Science Department and aut Poultry Science Oxford University Press 75/11(1996-11), 1428-1432 0032-5791 75:11<1428 1996 75 ps https://doi.org/10.3382/ps.0751428 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.3382/ps.0751428 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- LATOUR MICKEY A. 3To whom correspondence should be addressed aut NATIONALLICENCE 700 1- LAICHE S. A. College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi 39762 aut NATIONALLICENCE 700 1- THOMPSON J. R. Poultry Science Department and aut NATIONALLICENCE 700 1- POND A. L. College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi 39762 aut NATIONALLICENCE 700 1- PEEBLES E. DAVID Poultry Science Department and aut NATIONALLICENCE 773 0- Poultry Science Oxford University Press 75/11(1996-11), 1428-1432 0032-5791 75:11<1428 1996 75 ps Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford