caa a22 4500 397568282 CHVBK 20180308164834.0 cr unu---uuuuu 161202e199608 xx s 000 0 eng 10.3382/ps.0750954 doi (NATIONALLICENCE)oxford-10.3382/ps.0750954 Frequencies and Genetic Diversity of Major Histocompatibility Complex Class II Haplotypes in Commercial Turkey Lines [Elektronische Daten] [JIANGTAO ZHU, KARL E. NESTOR, YUXIN TANG] The purpose of the present study was to estimate frequencies and diversity of MHC haplotypes in primary breeding lines of commercial turkeys. Restriction fragment length polymorphism analysis was used to assay MHC Class II haplotypes of blood samples from 11 primary breeding lines (comprised of both sire and dam lines) contributed by three major turkey breeding companies. Twenty-five blood samples obtained from wild turkeys were included for comparison. Seven haplotypes previously identified in experimental turkey lines were detected in the commercial lines. One haplotype, A, was predominant in all commercial lines with an average frequency of 76% and in the wild turkeys with a frequency of 46%. Diversity of MHC haplotypes was reduced in the commercial lines compared with the wild turkey. Seven commercial lines had no more than four haplotypes and loci in some lines were close to fixation. Haplotypic frequencies among sire and dam lines differed significantly, but genetic diversity was not different. Only Haplotype D was significantly more frequent in sire than in dam lines. The present data demonstrate that genetic diversity at MHC loci was low in commercial turkey lines. © 1996 Poultry Science Association, Inc. Breeding and Genetics nationallicence major histocompatibility complex nationallicence Class II haplotypes nationallicence frequencies nationallicence genetic diversity nationallicence commercial turkey lines nationallicence ZHU JIANGTAO aut NESTOR KARL E. 2To whom correspondence should be addressed. aut TANG YUXIN aut Poultry Science Oxford University Press 75/8(1996-08), 954-958 0032-5791 75:8<954 1996 75 ps https://doi.org/10.3382/ps.0750954 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.3382/ps.0750954 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- ZHU JIANGTAO aut NATIONALLICENCE 700 1- NESTOR KARL E. 2To whom correspondence should be addressed aut NATIONALLICENCE 700 1- TANG YUXIN aut NATIONALLICENCE 773 0- Poultry Science Oxford University Press 75/8(1996-08), 954-958 0032-5791 75:8<954 1996 75 ps Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford