caa a22 4500 397568533 CHVBK 20180308164834.0 cr unu---uuuuu 161202e199612 xx s 000 0 eng 10.3382/ps.0751463 doi (NATIONALLICENCE)oxford-10.3382/ps.0751463 Associations of Individual Genomic Heterozygosity, Estimated by Molecular Fingerprinting, and of Dam Major Histocompatibility Complex with Growth and Egg Production Traits in Layer Chickens [Elektronische Daten] [A. CAHANER, E. J. SMITH, S. SWENSON, S. J. LAMONT] Growth and egg production data from F2 layer chickens produced from a mating of MHC-heterozygous B 15 B 44 sires to B 15 B 44 and B 15 B 43 dams were analyzed for associations with the level of the individual's genomic heterozygosity and dam MHC. The F1 sires and dams were produced from matings of birds from two genetically distinct, highly inbred lines. Genomic heterozygosity (expressed as composite band frequency, CBF) was estimated based on the average proportion of shared bands of individual birds compared to a composite pool of Hinf I-digested DNA samples from the two inbred lines. Birds from dams of genotype B 15 B 43 had significantly greater BW than progeny from B 15 B 44 dams at 6 wk and thereafter. Dam MHC genotype differences were also significant for number of eggs laid from 20 to 28 wk of age, with B 15 B 43 progeny being superior. Negative regression coefficients at hatch, 32, and 44 wk were observed for the effect of CBF on BW of progeny from B 15 B 43 dams and at hatch and 32 wk from progeny of pooled dam genotypes. Similarly, negative regression coefficients were observed for the association of CBF with number of eggs within progeny from the B 15 B 44 dam MHC genotypes at 20 to 28 wk and total period recorded, and at 28 to 36 wk for progeny from B 15 B 43 dams. The CBF regression coefficients and the differences among progeny based on dam MHC genotypes suggest that individual heterozygosity and MHC genotype may be associated with BW and egg production in chickens. © 1996 Poultry Science Association, Inc. Breeding and Genetics nationallicence egg traits nationallicence body weight nationallicence major histocompatibility complex nationallicence DNA fingerprinting nationallicence heterozygosity nationallicence CAHANER A. aut SMITH E. J. aut SWENSON S. aut LAMONT S. J. 4To whom correspondence should be addressed. aut Poultry Science Oxford University Press 75/12(1996-12), 1463-1467 0032-5791 75:12<1463 1996 75 ps https://doi.org/10.3382/ps.0751463 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.3382/ps.0751463 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- CAHANER A. aut NATIONALLICENCE 700 1- SMITH E. J. aut NATIONALLICENCE 700 1- SWENSON S. aut NATIONALLICENCE 700 1- LAMONT S. J. 4To whom correspondence should be addressed aut NATIONALLICENCE 773 0- Poultry Science Oxford University Press 75/12(1996-12), 1463-1467 0032-5791 75:12<1463 1996 75 ps Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford