caa a22 4500 397569262 CHVBK 20180308164836.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.3382/ps.0750627 doi (NATIONALLICENCE)oxford-10.3382/ps.0750627 Age-Related Changes of Protein Turnover in Specific Tissues of the Chick [Elektronische Daten] [S. TESSERAUD, R. PERESSON, A. M. CHAGNEAU] The effect of age on muscle and liver protein turnover was analyzed in growing broilers. Protein turnover was compared in the Pectoralis major (PM), the Anterior Latissimus dorsi (ALD), and the Sartorius (SART) muscles, as well as in the liver in broilers at three ages (2, 3, and 4 wk). Protein fractional synthesis rates (FSR, in percentage per day) were measured by a flooding dose of L-[4-3H] Phe. Protein fractional breakdown rates (FBR, in percentage per day) were estimated as the difference between FSR and the gain rates of tissue protein. When expressed in absolute rates (grams per day), tissue protein deposition increased during chick growth (approximately 1.7-fold, whatever the tissue). This phenomenon was accompanied by increased protein synthesis (ASR) and proteolysis (ABR) in the PM and in the ALD muscles as well as in the liver. However, ASR and ABR did not seem to be significantly modified in SART. The FSR in skeletal muscles significantly decreased with age. This developmental decline was associated with decreases in RNA content and RNA:protein ratio (Cs, capacity for protein synthesis). In contrast to muscle, we found no significant variation in liver FSR between 2 and 4 wk of age. In addition, liver Cs and translational efficiencies were not decreased. Finally, in muscle as in liver, FBR did not show any clear age-related pattern. © 1996 Poultry Science Association, Inc. Metabolism and Nutrition nationallicence age nationallicence protein turnover nationallicence skeletal muscles nationallicence liver nationallicence chick nationallicence TESSERAUD S. aut PERESSON R. aut CHAGNEAU A. M. aut Poultry Science Oxford University Press 75/5(1996-05), 627-631 0032-5791 75:5<627 1996 75 ps https://doi.org/10.3382/ps.0750627 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.3382/ps.0750627 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- TESSERAUD S. aut NATIONALLICENCE 700 1- PERESSON R. aut NATIONALLICENCE 700 1- CHAGNEAU A. M. aut NATIONALLICENCE 773 0- Poultry Science Oxford University Press 75/5(1996-05), 627-631 0032-5791 75:5<627 1996 75 ps Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford