caa a22 4500 397569688 CHVBK 20180308164837.0 cr unu---uuuuu 161202e199610 xx s 000 0 eng 10.1093/oxfordjournals.jmicro.a023461 doi (NATIONALLICENCE)oxford-10.1093/oxfordjournals.jmicro.a023461 Morphological and Cytoskeletal Changes in Endothelial Cells of Vein Grafts under Arterial Hemodynamic Conditions In Vivo [Elektronische Daten] [Kazumi Yoshida, Keiji Sugimoto] To understand venous endothelial adaptation to arterial hemodynamics in vivo, changes in surface morphology and stress fiber distribution in the endothelial cells of an autologous vein graft transplanted to a rabbit femoral artery were investigated by scanning electron microscopy and confocal laser scanning microscopy, respectively. After transplantation, the shape index (length of cellular long axis/short axis) of the endothelial cells in the graft was intermediate between those of control arteries and veins, and persisted almost unchanged up to week 16. In contrast, the expression of intracellular stress fibers changed; stress fibers of the endothelial cells in the graft were rare shortly after the operation, but gradually developed and increased both in number and thickness, to a level similar to that in the control arterial endothelial cells by week 16. These results suggest that venous endothelial cells, subjected to hemodynamic change, maintain their shape through stress fiber development. © 1996 Oxford University Press Full-length Papers nationallicence stress fiber nationallicence vein graft nationallicence endothelial cells nationallicence scanning electron microscopy nationallicence confocal laser scanning microscopy nationallicence Yoshida Kazumi Department of Surgery. The Jikei University School of Medicine 3-25-8 Nishi-shinbashl. Minato-ku, Tokyo, 105 Japan aut Sugimoto Keiji Department of Anatomy, Nippon Medical School 1-1-5 Sendagi, Bunkyo-kv, Tokyo, 113 Japan aut Microscopy Oxford University Press 45/5(1996-10), 428-435 0022-0744 45:5<428 1996 45 jmicro https://doi.org/10.1093/oxfordjournals.jmicro.a023461 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/oxfordjournals.jmicro.a023461 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yoshida Kazumi Department of Surgery. The Jikei University School of Medicine 3-25-8 Nishi-shinbashl. Minato-ku, Tokyo, 105 Japan aut NATIONALLICENCE 700 1- Sugimoto Keiji Department of Anatomy, Nippon Medical School 1-1-5 Sendagi, Bunkyo-kv, Tokyo, 113 Japan aut NATIONALLICENCE 773 0- Microscopy Oxford University Press 45/5(1996-10), 428-435 0022-0744 45:5<428 1996 45 jmicro Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford