caa a22 4500 397574959 CHVBK 20180308164852.0 cr unu---uuuuu 161202e199606 xx s 000 0 eng 10.1093/hmg/5.6.853 doi (NATIONALLICENCE)oxford-10.1093/hmg/5.6.853 A Gene for Autosomal Dominant Late-Onset Progressive Non-Syndromic Hearing Loss, DFNA10, Maps to Chromosome 6 [Elektronische Daten] [Marsha E. O'Neill, Jacquie Marietta, Darryl Nishimura, Sigrid Wayne, Guy Van Camp, Lut Van Laer, Clelia Negrini, Edward R. Wilcox, Achih Chen, Kunihiro Fukushima, Li Ni, Val C. Sheffield, Richard J. H. Smith] Late-onset non-syndromic hearing impairment is the most common type of neurological dysfunction in the elderly. It can be either acquired or inherited, although the relative impact of heredity on this type of loss is not known. To date, nine different genes have been localized, but none has been cloned. Using an extended American family in which a gene for autosomal dominant late-onset non-syndromic hearing impairment is segregating, we have identified a new locus, DFNA10, on chromosome 6. © 1996 Oxford University Press O'Neill Marsha E. Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut Marietta Jacquie Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut Nishimura Darryl Department of Pediatrics, University of Iowa, Iowa City, Iowa, 52242, USA aut Wayne Sigrid Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut Van Camp Guy Department of Medical Genetics, University of Antwerp (UIA), 2610 Antwerpen, Belgium aut Van Laer Lut Department of Medical Genetics, University of Antwerp (UIA), 2610 Antwerpen, Belgium aut Negrini Clelia National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, 20850, USA aut Wilcox Edward R. National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, 20850, USA aut Chen Achih Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut Fukushima Kunihiro Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut Ni Li Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut Sheffield Val C. Department of Pediatrics, University of Iowa, Iowa City, Iowa, 52242, USA aut Smith Richard J. H. Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut Human Molecular Genetics Oxford University Press 5/6(1996-06), 853-856 0964-6906 5:6<853 1996 5 hmg https://doi.org/10.1093/hmg/5.6.853 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/hmg/5.6.853 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- O'Neill Marsha E. Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Marietta Jacquie Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Nishimura Darryl Department of Pediatrics, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Wayne Sigrid Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Van Camp Guy Department of Medical Genetics, University of Antwerp (UIA), 2610 Antwerpen, Belgium aut NATIONALLICENCE 700 1- Van Laer Lut Department of Medical Genetics, University of Antwerp (UIA), 2610 Antwerpen, Belgium aut NATIONALLICENCE 700 1- Negrini Clelia National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, 20850, USA aut NATIONALLICENCE 700 1- Wilcox Edward R. National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, 20850, USA aut NATIONALLICENCE 700 1- Chen Achih Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Fukushima Kunihiro Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Ni Li Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Sheffield Val C. Department of Pediatrics, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 700 1- Smith Richard J. H. Department of Otolaryngology, University of Iowa, Iowa City, Iowa, 52242, USA aut NATIONALLICENCE 773 0- Human Molecular Genetics Oxford University Press 5/6(1996-06), 853-856 0964-6906 5:6<853 1996 5 hmg Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford