caa a22 4500 397581556 CHVBK 20180308164908.0 cr unu---uuuuu 161202e199611 xx s 000 0 eng 10.1093/cercor/6.6.789 doi (NATIONALLICENCE)oxford-10.1093/cercor/6.6.789 Axonal Processes and Neural Plasticity. II: Adult Somatosensory Maps [Elektronische Daten] [T. Elliott, C. I. Howarth, N. R. Shadbolt] Following our recent presentation of an axonal process sprouting and retraction framework for ocular dominance column formation, we now apply it, unchanged, to address issues of adult somato-sensory map plasticity. Specifically, we model the rearrangement of S-I in adult rodents following denervation of a row of vibrissae, and the rearrangement of area 3b in adult monkeys following hyper-stimulation of a digit. While we do not attempt to capture the rapid changes which occur as the result of unmasking or potentiating existing connections, we demonstrate that axonal process sprouting and retraction is a possible mechanism mediating many of the long-term changes induced by anomalous peripheral activity. A significant feature of our framework, demonstrated by this study, is that it can account for plasticity in both developing and mature systems, and in different sensory modalities. In contrast, synapse-specific Hebbian models with synaptic normalization, which employ anatomically fixed connections capable of changes in efficacy, may not be able to account for both developmental and adult plasticity without the form of the imposed normalization, which enforces competition between afferents, being changed. © 1996 Oxford University Press Articles nationallicence Elliott T. Department of Psychology, University of Nottingham, Nottingham NG7 2RD, UK aut Howarth C. I. Department of Psychology, University of Nottingham, Nottingham NG7 2RD, UK aut Shadbolt N. R. Department of Psychology, University of Nottingham, Nottingham NG7 2RD, UK aut Cerebral Cortex Oxford University Press 6/6(1996-11), 789-793 1047-3211 6:6<789 1996 6 cercor https://doi.org/10.1093/cercor/6.6.789 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/cercor/6.6.789 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Elliott T. Department of Psychology, University of Nottingham, Nottingham NG7 2RD, UK aut NATIONALLICENCE 700 1- Howarth C. I. Department of Psychology, University of Nottingham, Nottingham NG7 2RD, UK aut NATIONALLICENCE 700 1- Shadbolt N. R. Department of Psychology, University of Nottingham, Nottingham NG7 2RD, UK aut NATIONALLICENCE 773 0- Cerebral Cortex Oxford University Press 6/6(1996-11), 789-793 1047-3211 6:6<789 1996 6 cercor Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence SWISSBIB 397581548 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford