caa a22 4500 397581750 CHVBK 20180308164909.0 cr unu---uuuuu 161202e199603 xx s 000 0 eng 10.1093/cercor/6.2.311 doi (NATIONALLICENCE)oxford-10.1093/cercor/6.2.311 Prefrontal Cortex and Working Memory for Spatial Response, Spatial Location, and Visual Object Information in the Rat [Elektronische Daten] [Raymond P. Kesner, Mary E. Hunt, Joseph M. Williams, Jeffrey M. Long] In the first experiment, rats were trained on a working memory task for a spatial response (right-left turn) information using a delayed matching-to-sample procedure. Following lesions of the medial prefrontal cortex (MPF), which includes anterior cingulate and medial precentral cortex, there was a profound working memory deficit even at the shortest delay. In the second experiment, rats were trained on a working memory task for spatial location information using a delayed matching-to-sample procedure. Following lesions of the MPF, there was only a mild working memory deficit, whereas following dorsal hippocampal lesions there was a profound working memory deficit even at the shortest delay. In the third experiment, rats were trained on a working memory task for visual object information using a delayed nonmatching-to-sample procedure. Following lesions of the MPF, there were no working memory deficits, whereas following lesions of the prelimbic and infralimbic cortex there was a profound working memory deficit even at the shortest delay. The results suggest that different neural subregions of the prefrontal cortex mediate working memory for specific attribute information. © 1996 Oxford University Press Articles nationallicence Kesner Raymond P. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut Hunt Mary E. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut Williams Joseph M. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut Long Jeffrey M. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut Cerebral Cortex Oxford University Press 6/2(1996-03), 311-318 1047-3211 6:2<311 1996 6 cercor https://doi.org/10.1093/cercor/6.2.311 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/cercor/6.2.311 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kesner Raymond P. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut NATIONALLICENCE 700 1- Hunt Mary E. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut NATIONALLICENCE 700 1- Williams Joseph M. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut NATIONALLICENCE 700 1- Long Jeffrey M. Department of Psychology, University of Utah, Salt Lake City Utah 84112 aut NATIONALLICENCE 773 0- Cerebral Cortex Oxford University Press 6/2(1996-03), 311-318 1047-3211 6:2<311 1996 6 cercor Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford