caa a22 4500 397581815 CHVBK 20180308164909.0 cr unu---uuuuu 161202e199601 xx s 000 0 eng 10.1093/cercor/6.1.39 doi (NATIONALLICENCE)oxford-10.1093/cercor/6.1.39 Object and Spatial Visual Working Memory Activate Separate Neural Systems in Human Cortex [Elektronische Daten] [Susan M. Courtney, Leslie G. Ungerleider, Katrina Keil, James V. Haxby] Human and nonhuman primate visual systems are divided into object and spatial information processing pathways. In the macaque, it has been shown that these pathways project to separate areas in the frontal lobe and that the ventral and dorsal frontal areas are, respectively, involved in working memory for objects and spatial locations. A positron emission tomography (PET) study was done to determine if a similar anatomical segregation exists in humans for object and spatial visual working memory. Face working memory demonstrated significant increases in regional cerebral blood flow (rCBF), relative to location working memory, in fusiform, parahippocampal, inferior frontal, and anterior cingulate cortices, and in right thalamus and midline cerebellum. Location working memory demonstrated significant increases in rCBF, relative to face working memory, in superior and inferior parietal cortex, and in the superior frontal sulcus. Our results show that the neural systems involved in working memory for faces and for spatial location are functionally segregated, with different areas recruited in both extrastriate and frontal cortices for processing the two types of visual information. © 1996 Oxford University Press Articles nationallicence Courtney Susan M. Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut Ungerleider Leslie G. Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut Keil Katrina Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut Haxby James V. Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut Cerebral Cortex Oxford University Press 6/1(1996-01), 39-49 1047-3211 6:1<39 1996 6 cercor https://doi.org/10.1093/cercor/6.1.39 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/cercor/6.1.39 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Courtney Susan M. Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut NATIONALLICENCE 700 1- Ungerleider Leslie G. Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut NATIONALLICENCE 700 1- Keil Katrina Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut NATIONALLICENCE 700 1- Haxby James V. Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Maryland 20892 aut NATIONALLICENCE 773 0- Cerebral Cortex Oxford University Press 6/1(1996-01), 39-49 1047-3211 6:1<39 1996 6 cercor Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford