caa a22 4500 397581882 CHVBK 20180308164909.0 cr unu---uuuuu 161202e199609 xx s 000 0 eng 10.1093/cercor/6.5.661 doi (NATIONALLICENCE)oxford-10.1093/cercor/6.5.661 Interhemispheric Anatomical Differences in Human Primary Auditory Cortex: Probabilistic Mapping and Volume Measurement from Magnetic Resonance Scans [Elektronische Daten] [V. B. Penhune, R. J. Zatorre, J. D. MacDonald, A. C. Evans] The gyral morphology of the region of the primary auditory cortex (PAC) in the human brain is highly variable, and possible asymmetries between the hemispheres have been noted since the beginning of the century. We mapped the location and extent of PAC as identified from gross anatomical landmarks in magnetic resonance scans that had been transformed into Talairach-Tournoux stereotaxic space. Individual maps were averaged to produce a probabilistic map of the region which can be co-registered with any image of brain structure or function that has been similarly transformed. The map can be used to localize a region of interest, such as a lesion, or an activation focus from positron emission tomography or functional magnetic resonance imaging, within a specified range of probability. We also measured the total volume of the region and found a significant L>R asymmetry both on average and in the majority of subjects. Automatic segmentation of the volumes into grey and white matter revealed larger volumes of white, but not grey matter on the left. This larger volume of cortical connecting fibres may be related to the known left-hemisphere dominance for speech, and a preferential role for left PAC in processing temporal aspects of auditory stimuli is suggested. © 1996 Oxford University Press Articles nationallicence Penhune V. B. Department of Neuropsychology and Cognitive Neuroscience, McGill University Montreal, Quebec, Canada aut Zatorre R. J. Department of Neuropsychology and Cognitive Neuroscience, McGill University Montreal, Quebec, Canada aut MacDonald J. D. McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University Montreal, Quebec, Canada aut Evans A. C. McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University Montreal, Quebec, Canada aut Cerebral Cortex Oxford University Press 6/5(1996-09), 661-672 1047-3211 6:5<661 1996 6 cercor https://doi.org/10.1093/cercor/6.5.661 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/cercor/6.5.661 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Penhune V. B. Department of Neuropsychology and Cognitive Neuroscience, McGill University Montreal, Quebec, Canada aut NATIONALLICENCE 700 1- Zatorre R. J. Department of Neuropsychology and Cognitive Neuroscience, McGill University Montreal, Quebec, Canada aut NATIONALLICENCE 700 1- MacDonald J. D. McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University Montreal, Quebec, Canada aut NATIONALLICENCE 700 1- Evans A. C. McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University Montreal, Quebec, Canada aut NATIONALLICENCE 773 0- Cerebral Cortex Oxford University Press 6/5(1996-09), 661-672 1047-3211 6:5<661 1996 6 cercor Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford