caa a22 4500 397581955 CHVBK 20180308164909.0 cr unu---uuuuu 161202e199607 xx s 000 0 eng 10.1093/cercor/6.4.612 doi (NATIONALLICENCE)oxford-10.1093/cercor/6.4.612 Active Representation of Shape and Spatial Location in Man [Elektronische Daten] [S. C. Baker, C. D. Frith, S. J. Frackowiak, R. J. Dolan] Neural activity during the delay period of spatial delayed response (DR) and delayed matching (DM) tasks was investigated by positron emission tomography. A distributed cortical system was activated in each condition. The bilateral dorsolateral prefrontal cortex (DLPFC) was activated in the delay period of both tasks; activation was of higher significance on the right in the DR task and the left in the DM task, and extended to the anterolateral prefrontal cortex in the DM condition. Active representation of spatial location in the DR task was associated with co-activation of the medial and lateral parietal cortex and the extrastriate visual cortex. Active representation of shape in the DM task was associated with co-activation of the medial and lateral parietal cortex and the inferior temporal cortex. Response-related activity was observed in both tasks. Activation of anterior cingulate, inferior frontal, lateral premotor and rostral inferior parietal cortex was observed in the DR condition, a task characterized by preparation of a movement to a predetermined location. In contrast, preparation to move to an undetermined location in the DM task was associated with activation predominantly in rostral SMA. © 1996 Oxford University Press Articles nationallicence Baker S. C. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut Frith C. D. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut Frackowiak S. J. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut Dolan R. J. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut Cerebral Cortex Oxford University Press 6/4(1996-07), 612-619 1047-3211 6:4<612 1996 6 cercor https://doi.org/10.1093/cercor/6.4.612 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/cercor/6.4.612 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Baker S. C. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut NATIONALLICENCE 700 1- Frith C. D. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut NATIONALLICENCE 700 1- Frackowiak S. J. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut NATIONALLICENCE 700 1- Dolan R. J. Wellcome Department of Cognitive Neurology, Institute of Neurology, WC1N 3BG and MRC Cyclotron Unit, Hammersmith Hospital London W12 OHS aut NATIONALLICENCE 773 0- Cerebral Cortex Oxford University Press 6/4(1996-07), 612-619 1047-3211 6:4<612 1996 6 cercor Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford