caa a22 4500 397590423 CHVBK 20180308164937.0 cr unu---uuuuu 161202e199612 xx s 000 0 eng 10.1093/jac/38.6.1085 doi (NATIONALLICENCE)oxford-10.1093/jac/38.6.1085 Killing kinetics of meropenem against penicillin-resistant pneumococci [Elektronische Daten] [V. Barakett, D. Lesage, F. Delisle, G. Richard, J. C. Petit] The killing kinetics of meropenem against sixteen clinical isolates of pneumococci (12 penicillin-resistant, three penicillin-intermediate and one penicillin-sensitive) were studied. Meropenem was tested at 1x, 2x and 4x the MIC for each individual isolate. The results showed a good bactericidal activity with rapid killing of pneumococci (killing > 3 log10 cfu/mL was obtained for nine strains). This strategy needs clinical assessment and might prove to be a suitable alternative to penicillin and cephalosporins for the treatment of mixed infections involving multiresistant pneumococci. © 1996 by the British Society for Antimicrobial Chemotherapy Brief reports nationallicence Barakett V. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut Lesage D. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut Delisle F. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut Richard G. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut Petit J. C. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut Journal of Antimicrobial Chemotherapy Oxford University Press 38/6(1996-12), 1085-1089 0305-7453 38:6<1085 1996 38 jac https://doi.org/10.1093/jac/38.6.1085 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/38.6.1085 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Barakett V. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut NATIONALLICENCE 700 1- Lesage D. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut NATIONALLICENCE 700 1- Delisle F. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut NATIONALLICENCE 700 1- Richard G. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut NATIONALLICENCE 700 1- Petit J. C. Laboraloire Central de Microbiologie-CHU Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 38/6(1996-12), 1085-1089 0305-7453 38:6<1085 1996 38 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford