caa a22 4500 397590539 CHVBK 20180308164937.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.1093/jac/37.5.1011 doi (NATIONALLICENCE)oxford-10.1093/jac/37.5.1011 Comparative in-vitro activity of the new fluoroquinolone trovafloxacin (CP-99,219) against Gram-positive cocci [Elektronische Daten] [Teresa M. Coque, Kavindra V. Singh, Barbara E. Murray] The in-vitro activities of the new fluoroquinolone trovafloxacin (CP-99,219) and ciprofloxacin were determined against 225 Gram-positive cocci. Trovafloxacin was 4-32 fold more active than ciprofloxacin against staphylococci and streptococci and also showed greater activity against enterococci including vancomycin resistant Enterococcus faecium and Enterococcus faecalis that were highly resistant to aminoglycosides and/or produced β-lactamase. Trovafloxacin was also bactericidal at 3 mg/L against enterococci except for isolates for which the MICs were ≥2 mg/L. © 1996 The British Society for Antimicrobial Chemotherapy Brief reports nationallicence Coque Teresa M. Division of Infectious Diseases, Departments of Internal Medicine, The University of Texas Medical School Houston, Texas 77030, USA aut Singh Kavindra V. Division of Infectious Diseases, Departments of Internal Medicine, The University of Texas Medical School Houston, Texas 77030, USA aut Murray Barbara E. Division of Infectious Diseases, Departments of Internal Medicine, The University of Texas Medical School Houston, Texas 77030, USA aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/5(1996-05), 1011-1016 0305-7453 37:5<1011 1996 37 jac https://doi.org/10.1093/jac/37.5.1011 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.5.1011 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Coque Teresa M. Division of Infectious Diseases, Departments of Internal Medicine, The University of Texas Medical School Houston, Texas 77030, USA aut NATIONALLICENCE 700 1- Singh Kavindra V. Division of Infectious Diseases, Departments of Internal Medicine, The University of Texas Medical School Houston, Texas 77030, USA aut NATIONALLICENCE 700 1- Murray Barbara E. Division of Infectious Diseases, Departments of Internal Medicine, The University of Texas Medical School Houston, Texas 77030, USA aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/5(1996-05), 1011-1016 0305-7453 37:5<1011 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford