caa a22 4500 397590660 CHVBK 20180308164937.0 cr unu---uuuuu 161202e199601 xx s 000 0 eng 10.1093/jac/37.1.175 doi (NATIONALLICENCE)oxford-10.1093/jac/37.1.175 An audit of the use of antifungal agents [Elektronische Daten] [Félix Gutiérrez, Patrick G. Wall, Jonathan Cohen] A three month prospective audit of systemic antifungal therapy was undertaken in a university hospital in the United Kingdom to determine the patterns of usage of systemic antifungal drugs. The case notes of all patients receiving systemic antifungal agents were reviewed daily and the appropriateness of therapy was determined according to standards in the authoritative literature. One hundred and fifteen courses of treatment with antifungal agents for 1481 days were administered to 74 patients. When a patient had received more than one course of antifungals, both the individual courses and the combination of courses, i.e. a regimen, were judged. Antifungal agents were given as an empirical therapy or as prophylaxis in 68% of the courses, with fluconazole and amphotericin B desoxycholate being the agents most frequently used. Therapy was considered unconventional in 26.9% of the courses and 40.5% of the regimens, mainly because either the indication or the duration of treatment did not conform to conventional practice. Improvement in prescribing practices and standards for ongoing audit can only be achieved if a consensus can be reached on how these agents can be used appropriately. © 1996 The British Society for Antimicrobial Chemotherapy Antimicrobial practice nationallicence Gutiérrez Félix Servicio de Medicina Interna-Infecciosas, Hospital SVS Marina Baixa 03570 Villajoyosa, Alicante, Spain aut Wall Patrick G. PHLS Communicable Disease Surveillance Centre 61 Colindale Avenue, London NW9 5EQ, UK aut Cohen Jonathan Department of Infectious Diseases and Bacteriology, Royal Postgraduate Medical School, Hammersmith Hospital Du Cane Road, London W120NN, UK aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/1(1996-01), 175-185 0305-7453 37:1<175 1996 37 jac https://doi.org/10.1093/jac/37.1.175 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.1.175 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gutiérrez Félix Servicio de Medicina Interna-Infecciosas, Hospital SVS Marina Baixa 03570 Villajoyosa, Alicante, Spain aut NATIONALLICENCE 700 1- Wall Patrick G. PHLS Communicable Disease Surveillance Centre 61 Colindale Avenue, London NW9 5EQ, UK aut NATIONALLICENCE 700 1- Cohen Jonathan Department of Infectious Diseases and Bacteriology, Royal Postgraduate Medical School, Hammersmith Hospital Du Cane Road, London W120NN, UK aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/1(1996-01), 175-185 0305-7453 37:1<175 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford