caa a22 4500 397590792 CHVBK 20180308164938.0 cr unu---uuuuu 161202e199601 xx s 000 0 eng 10.1093/jac/37.1.85 doi (NATIONALLICENCE)oxford-10.1093/jac/37.1.85 Increasing ciprofloxacin resistance in salmonellas in England and Wales 1991-1994 [Elektronische Daten] [J. A. Frost, A. Kelleher, B. Rowe] Ciprofloxacin is now widely used as the drug of choice for those severe salmonella infections where antibiotic therapy is indicated. Between 1991 and 1994 ciprofloxacin resistance in salmonellas isolated from humans in England and Wales increased from 0.3% to 2.1%. Among the most prevalent serotypes the highest incidence was seen in Salmonella hadar where ciprofloxacin resistance has increased from 2.0% in 1991 to 39.6% in 1994. The incidence of ciprofloxacin resistance remains uncommon in other serotypes and in 1994 5.1% of Salmonella virchow and Salmonella newport were resistant compared with 1.4% of Salmonella typhimurium and 0.4% of Salmonella enteritidis. There has been a number of examples of development of resistance to quinolone drugs during treatment of human infections. Ciprofloxacin resistance also occurs in salmonellas isolated from food animals and human food. This increasing incidence of ciprofloxacin resistance reflects the more widespread use of fluoroquinolone drugs in both humans and food animals. © 1996 The British Society for Antimicrobial Chemotherapy Original articles nationallicence Frost J. A. Laboratory of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT, UK aut Kelleher A. Laboratory of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT, UK aut Rowe B. Laboratory of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT, UK aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/1(1996-01), 85-91 0305-7453 37:1<85 1996 37 jac https://doi.org/10.1093/jac/37.1.85 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.1.85 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Frost J. A. Laboratory of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT, UK aut NATIONALLICENCE 700 1- Kelleher A. Laboratory of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT, UK aut NATIONALLICENCE 700 1- Rowe B. Laboratory of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT, UK aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/1(1996-01), 85-91 0305-7453 37:1<85 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford