caa a22 4500 397591012 CHVBK 20180308164938.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.1093/jac/37.suppl_B.171 doi (NATIONALLICENCE)oxford-10.1093/jac/37.suppl_B.171 Bird A. G. Department of Immunology, Churchill Hospital, Oxford OX3 7LJ, UK Non-HIV AIDS: nature and strategies for its management [Elektronische Daten] [A. G. Bird] Despite initial claims to the contrary, a cluster of reports of severe opportunistic infections occurring in patients without evidence of HIV infection do not appear to represent a new disease entity or present evidence of epidemiologically associated cases suggesting an infectious agent. Reported cases are reviewed and appear to represent a heterogeneous group, many of which may represent sporadic cases of late onset acquired immunodeficiency. In addition, a small group of asymptomatic subjects have been identified with constitutively low CD4 T cell populations which appear to have little or no clinical significance since these patients have no evidence of clinical immunodeficiency. Newly identified cases should be fully investigated immunologically and virologically after recovery from their presenting infection and continuous or prophylactic therapy instituted only in cases of substantiated long-term severe immunodeficiency. © 1996 The British Society for Antimicrobial Chemotherapy Articles nationallicence Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 171-183 0305-7453 37<171 1996 37 jac https://doi.org/10.1093/jac/37.suppl_B.171 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.suppl_B.171 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Bird A. G. Department of Immunology, Churchill Hospital, Oxford OX3 7LJ, UK NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 171-183 0305-7453 37<171 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford