caa a22 4500 397591055 CHVBK 20180308164938.0 cr unu---uuuuu 161202e199603 xx s 000 0 eng 10.1093/jac/37.3.457 doi (NATIONALLICENCE)oxford-10.1093/jac/37.3.457 Mobile rRNA methylase genes coding for erythromycin resistance in Actinobacillus actinomycetemcomitans [Elektronische Daten] [D. E. Roe, A. Weinberg, M. C. Roberts] We found that 17 (68%) of 25 Actinobacillus actinomycetemcomitans isolated from periodontally diseased sites had MICs of erythromycin ≥8 mg/L. The isolates were hybridized with five rRNA methylase genes and gene mobility was determined. Twenty-four (96%) of 25 isolates hybridized with one or more rRNA methylase genes. Representative isolates were able to transfer erythromycin resistance to Haemophilus influenzae and Enterococcus faecalis recipients. The transconjugants were shown to carry rRNA methylase genes by DNA probe hybridization and had MICs of erythromycin 32 to 256 mg/L. © 1996 The British Society for Antimicrobial Chemotherapy Original articles nationallicence Roe D. E. Department of Pathobiology, University of Washington, Seattle, WA 98195, USA, Seattle, WA 98195, USA aut Weinberg A. Periodontics, University of Washington Seattle, WA 98195, USA aut Roberts M. C. Department of Pathobiology, University of Washington Seattle, WA 98195, USA aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/3(1996-03), 457-464 0305-7453 37:3<457 1996 37 jac https://doi.org/10.1093/jac/37.3.457 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.3.457 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Roe D. E. Department of Pathobiology, University of Washington, Seattle, WA 98195, USA, Seattle, WA 98195, USA aut NATIONALLICENCE 700 1- Weinberg A. Periodontics, University of Washington Seattle, WA 98195, USA aut NATIONALLICENCE 700 1- Roberts M. C. Department of Pathobiology, University of Washington Seattle, WA 98195, USA aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/3(1996-03), 457-464 0305-7453 37:3<457 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford