caa a22 4500 397591713 CHVBK 20180308164940.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.1093/jac/37.5.1017 doi (NATIONALLICENCE)oxford-10.1093/jac/37.5.1017 Concentration of teicoplanin in the serum of adults with end stage chronic renal failure undergoing treatment for infection [Elektronische Daten] [A. Mercatello, K. Jaber, D. Hillaire-Buys, B. Coronel, J. Berland, E. Despaux] We examined the adequacy of the following schedule for the administration of iv teicoplanin to patients with chronic renal failure: three doses of 6 mg/kg at 12 h intervals, a fourth dose 24 h later and then subsequent doses every 72 h. Eight infected patients undergoing dialysis were investigated, with serum antibiotic concentrations measured ten minutes before and one hour after administration. Mean trough concentrations were 6.9±3.1 mg/L on day two, 9.8±4.4 mg/L (day three), 9.2±4.8 mg/L (day six), 10.9±5.5 mg/L (day nine), 12.1±6.1 mg/L (day 12) and 14.8±8.0 mg/L (day 15). The proposed schedule achieved adequate trough serum teicoplanin concentrations by 48 h in six out of eight patients examined. The dosage regimen was well tolerated. © 1996 The British Society for Antimicrobial Chemotherapy Brief reports nationallicence Mercatello A. Department of Nephrology, H;ôpital Ed. Herriot 69437Lyon Cedex 03, France aut Jaber K. Department of Haemodialysis, H;ôpital Ste Marguerite 13009 Marseille, France aut Hillaire-Buys D. Pharmacology Department, H;ôpital Saint-Eloi 34295 Montpellier, France aut Coronel B. Department of Nephrology, H;ôpital Ed. Herriot 69437Lyon Cedex 03, France aut Berland J. Department of Haemodialysis, H;ôpital Ste Marguerite 13009 Marseille, France aut Despaux E. Bacteriological Service, H;ôpital Saint-Eloi 34295 Montpellier, France aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/5(1996-05), 1017-1021 0305-7453 37:5<1017 1996 37 jac https://doi.org/10.1093/jac/37.5.1017 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.5.1017 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mercatello A. Department of Nephrology, H;ôpital Ed. Herriot 69437Lyon Cedex 03, France aut NATIONALLICENCE 700 1- Jaber K. Department of Haemodialysis, H;ôpital Ste Marguerite 13009 Marseille, France aut NATIONALLICENCE 700 1- Hillaire-Buys D. Pharmacology Department, H;ôpital Saint-Eloi 34295 Montpellier, France aut NATIONALLICENCE 700 1- Coronel B. Department of Nephrology, H;ôpital Ed. Herriot 69437Lyon Cedex 03, France aut NATIONALLICENCE 700 1- Berland J. Department of Haemodialysis, H;ôpital Ste Marguerite 13009 Marseille, France aut NATIONALLICENCE 700 1- Despaux E. Bacteriological Service, H;ôpital Saint-Eloi 34295 Montpellier, France aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/5(1996-05), 1017-1021 0305-7453 37:5<1017 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford