caa a22 4500 397591772 CHVBK 20180308164940.0 cr unu---uuuuu 161202e199604 xx s 000 0 eng 10.1093/jac/37.4.831 doi (NATIONALLICENCE)oxford-10.1093/jac/37.4.831 Peripheral sensory disturbances related to treatment with fluoroquinolones [Elektronische Daten] [Karin Hedenmalm, Olav Spigset] The symptoms and possible risk factors of peripheral sensory disturbances related to fluoroquinolones are reviewed on the basis of 37 reports submitted to the Swedish Adverse Drug Reactions Advisory Committee. In 25 patients (68%), symptoms occurred within 1 week after start of treatment. Paraesthesia was the most common complaint and occurred in 81% of the cases. Fifty-one per cent of the reports concerned numbness/hypoaesthesia, 27% pain/hyperaesthesia and 11% muscle weakness. Seventy-one per cent of the patients recovered within 2 weeks after drug discontinuation. Possible predisposing factors were impaired renal function, diabetes, lymphatic malignancy and treatment with another drug known to cause neuropathy. © 1996 The British Society for Antimicrobial Chemotherapy Brief reports nationallicence Hedenmalm Karin Division of Clinical Pharmacology, Norrland University Hospital, S-901 85 Umea, Sweden aut Spigset Olav Division of Clinical Pharmacology, Norrland University Hospital, S-901 85 Umea, Sweden aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/4(1996-04), 831-837 0305-7453 37:4<831 1996 37 jac https://doi.org/10.1093/jac/37.4.831 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.4.831 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hedenmalm Karin Division of Clinical Pharmacology, Norrland University Hospital, S-901 85 Umea, Sweden aut NATIONALLICENCE 700 1- Spigset Olav Division of Clinical Pharmacology, Norrland University Hospital, S-901 85 Umea, Sweden aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/4(1996-04), 831-837 0305-7453 37:4<831 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford