caa a22 4500 397592094 CHVBK 20180308164941.0 cr unu---uuuuu 161202e199612 xx s 000 0 eng 10.1093/jac/38.6.1061 doi (NATIONALLICENCE)oxford-10.1093/jac/38.6.1061 Morrissey Ian Chemotherapy Research Unit, University of East London, Romford Road, London El5 4LZ, UK Bactericidal activity of trovafloxacin (CP-99,219) [Elektronische Daten] [Ian Morrissey] Trovafloxacin was found to be a typical quinolone producing a biphasic dose response against Escherichia coli, Staphylococcus aureus or Streptococcus pneumoniae. A reduced rate of kill was seen against Enterococcus faecalis, which is also typical of the quinolones. However, the bactericidal activity of trovafloxacin against S. aureus and S. pneumoniae was greater than most other quinolones previously tested. The enhanced bactericidal activity of trovafloxacin against S. aureus may be explained by the possession of a very strong bactericidal mechanism B. Trovafloxacin may prove to be a quinolone of choice against S. aureus infections. © 1996 by the British Society for Antimicrobial Chemotherapy Brief reports nationallicence Journal of Antimicrobial Chemotherapy Oxford University Press 38/6(1996-12), 1061-1066 0305-7453 38:6<1061 1996 38 jac https://doi.org/10.1093/jac/38.6.1061 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/38.6.1061 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Morrissey Ian Chemotherapy Research Unit, University of East London, Romford Road, London El5 4LZ, UK NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 38/6(1996-12), 1061-1066 0305-7453 38:6<1061 1996 38 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford