caa a22 4500 397592205 CHVBK 20180308164942.0 cr unu---uuuuu 161202e199604 xx s 000 0 eng 10.1093/jac/37.4.815 doi (NATIONALLICENCE)oxford-10.1093/jac/37.4.815 In-vitro antifungal activity of sertaconazole, bifonazole, ketoconazole, and miconazole against yeasts of the Candida genus [Elektronische Daten] [A. J. Carrilo-Muñoz, C. Tur, J. Torres, A. C. Seymour] The in-vitro antifungal activity of sertaconazole against 110 strains of Candida yeasts (50 Candida albicans, 15 Candida glabrata, 2 Candida guilliermodii, 8 Candida krusei, 1 Candida kefyr, 8 Candida parapsilosis and 26 Candida tropicalis) was assessed in comparison with bifonazole, ketoconazole, econazole and miconazole. The majority of the strains were clinical isolates; some reference strains were included. A commercial agar diffusion method (NeoSensitabs, Rosco, Taastrup, Denmark) in Shadomy's modified medium pH 7 was used. Using the manufacturer's criteria, 86.4% of the strains were classified as "sensitive” to sertaconazole. The only strain classified as "resistant” to sertaconazote was the control reference strain of C. albicans. The remaining strains were classified as moderately sensitive. The sensitivity/resistance percentages for the other antifungals tested were 75.5/1.8 for ketoconazole, 71.8/2.7 for miconazole, 63.7/13.6 for econazole, and 59.1/5.5 for bifonazole. Sertaconazole showed a higher antifungal activity than that of the other antimycotics, tested in vitro which was statistically significant (P<0.001), as well as a lower resistance rate than that of econazole, bifonazole and ketoconazole. © 1996 The British Society for Antimicrobial Chemotherapy Brief reports nationallicence Carrilo-Muñoz A. J. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut Tur C. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut Torres J. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut Seymour A. C. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/4(1996-04), 815-819 0305-7453 37:4<815 1996 37 jac https://doi.org/10.1093/jac/37.4.815 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.4.815 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Carrilo-Muñoz A. J. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut NATIONALLICENCE 700 1- Tur C. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut NATIONALLICENCE 700 1- Torres J. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut NATIONALLICENCE 700 1- Seymour A. C. Unitat de Micologia, Institut Municipal D'investigacio (IMIM), Universitat Autonoma de Barcelona, Avda. Dr. Aiguader 80, E-08003 Barcelona, Spain aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/4(1996-04), 815-819 0305-7453 37:4<815 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford