caa a22 4500 39759223X CHVBK 20180308164942.0 cr unu---uuuuu 161202e199610 xx s 000 0 eng 10.1093/jac/38.4.727 doi (NATIONALLICENCE)oxford-10.1093/jac/38.4.727 The in-vitro anti-rickettsial activity of macrolides [Elektronische Daten] [Avi Keysary, Avi Itzhaki, Ethan Rubinstein, Ctaaya Oron, Gershon Keren] The anti-rickettsial activity of azithromycin and clarithromycin was studied in Vero cells. The rate of rickettsial inhibition-growth caused by both macrolides was determined using rickettsial counts and ELISA. Both macrolides inhibited > 50% the growth of Rickettsia conorii and Rickettsia typhi at concentrations of 1.0 and 0.1 mg/L, respectively. The growth of Coxiella burnetii was inhibited to a rate of ≥50% at the concentrations of 0.01 and 1.0 mg/L of azithromycin and clarithromycin, respectively. © 1995 The British Society for Antimicrobial Chemotherapy Brief reports nationallicence Keysary Avi Department of Infectious Diseases, Israel Institute for Biological Research POB 19 Ness-Ziona aut Itzhaki Avi Asaf-Harofe Medical Center Zrifin aut Rubinstein Ethan Infectious Diseases Unit, Sheba Medical Center, Tel-Hashomer, Tel-Aviv University, School of Medicine Israel aut Oron Ctaaya Department of Infectious Diseases, Israel Institute for Biological Research POB 19 Ness-Ziona aut Keren Gershon Infectious Diseases Unit, Sheba Medical Center, Tel-Hashomer, Tel-Aviv University, School of Medicine Israel aut Journal of Antimicrobial Chemotherapy Oxford University Press 38/4(1996-10), 727-731 0305-7453 38:4<727 1996 38 jac https://doi.org/10.1093/jac/38.4.727 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/38.4.727 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Keysary Avi Department of Infectious Diseases, Israel Institute for Biological Research POB 19 Ness-Ziona aut NATIONALLICENCE 700 1- Itzhaki Avi Asaf-Harofe Medical Center Zrifin aut NATIONALLICENCE 700 1- Rubinstein Ethan Infectious Diseases Unit, Sheba Medical Center, Tel-Hashomer, Tel-Aviv University, School of Medicine Israel aut NATIONALLICENCE 700 1- Oron Ctaaya Department of Infectious Diseases, Israel Institute for Biological Research POB 19 Ness-Ziona aut NATIONALLICENCE 700 1- Keren Gershon Infectious Diseases Unit, Sheba Medical Center, Tel-Hashomer, Tel-Aviv University, School of Medicine Israel aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 38/4(1996-10), 727-731 0305-7453 38:4<727 1996 38 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford