caa a22 4500 397592523 CHVBK 20180308164942.0 cr unu---uuuuu 161202e199608 xx s 000 0 eng 10.1093/jac/38.2.271 doi (NATIONALLICENCE)oxford-10.1093/jac/38.2.271 The in-vitro activity of trovafloxacin and nine other antimicrobials against 413 anaerobic bacteria [Elektronische Daten] [K. E. Bowker, M. Wootton, H. A. Holt, D. S. Reeves, A. P. MacGowan] The in-vitro activity of trovafloxacin and nine other antimicrobials was determined for 413 non copy anaerobic clinical isolates. Trovafloxacin was the most active quinolone tested with an MIC90 of 0.5 mg/L against Gram-positive cocci (n = 75); MIC90 of 4 mg/L against Gram-positive bacilli (n = 151); MIC90 of 0.5 mg/L for Gram-negative cocci (n = 12) and MIC90 of 1 mg/L for Gram-negative bacilli (n = 175). Overall the MIC90 of trovafloxacin was 1 mg/L which was equivalent to co-amoxiclav and one dilution higher than that of imipencm. The other seven comparators, including clindamycin and metronidazole, had higher MIC90 values than trovafloxacin. Trovafloxacin is likely to have clinically useful activity against anaerobes from human infection. © 1996 by the British Society for Antimicrobial Chemotherapy Brief reports nationallicence Bowker K. E. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut Wootton M. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut Holt H. A. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut Reeves D. S. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut MacGowan A. P. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut Journal of Antimicrobial Chemotherapy Oxford University Press 38/2(1996-08), 271-281 0305-7453 38:2<271 1996 38 jac https://doi.org/10.1093/jac/38.2.271 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/38.2.271 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bowker K. E. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut NATIONALLICENCE 700 1- Wootton M. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut NATIONALLICENCE 700 1- Holt H. A. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut NATIONALLICENCE 700 1- Reeves D. S. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut NATIONALLICENCE 700 1- MacGowan A. P. Bristol Centre for Antimicrobial Research & Evaluation, Southmead Health Services NHS Trust and the University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, Brisol, BS10 5NB, UK aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 38/2(1996-08), 271-281 0305-7453 38:2<271 1996 38 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford