caa a22 4500 397592590 CHVBK 20180308164943.0 cr unu---uuuuu 161202e199608 xx s 000 0 eng 10.1093/jac/38.2.309 doi (NATIONALLICENCE)oxford-10.1093/jac/38.2.309 The influence of the opinion of an infectious disease consultant on the appropriateness of antibiotic treatment in a general hospital [Elektronische Daten] [J. Gómez, S. J. Conde Cavero, J. L. Hernández Cardona, M. L. Núñez, J. Ruiz Gómez, M. Canteras, M. Valdés] The antibiotics chosen in hospitals are not always the most appropriate. A comparative prospective study with sequential analysis was designed to assess how the opinion of an infectious disease consultant affected the clinical efficacy of antimicrobial treatment in a general hospital. We studied 250 patients who had microbiologically documented infections according to Center for Disease Control criteria. The patients were divided in two groups with similar initial characteristics. Group G1 comprised 100 patients without infectious disease consultation, and group G2 contained 150 patients with infectious disease consultation. The influence of the consultant's opinion was assessed as the percentage of initially appropriate treatments, and by the number of inappropriate ones that were changed after the microbiological reults were known. The appropriateness of initial treatment was significantly higher in group G2 (66% vs 55%), as were the number of treatments changed on the basis of the microbiological results (57.6% vs 33.3%). This lead to higher rates of cure, fewer deaths, and fewer cases of persistent infection in group G2. In 42.4% of G2 patients, antibiotic treatment was not changed in spite of the microbiological results and the opinion of an infectious disease consultant. We conclude that antibiotic treatment for the most clinically significant infections can be optimized if it is dispensed according to carefully developed guidelines. © 1996 by the British Society for Antimicrobial Chemotherapy Antimicrobial practice nationallicence Gómez J. Virgen de Arrixaca University Hospital, Infectious Diseases Unit 30100 Espinardo, Murcia, Spain aut Cavero S. J. Conde Virgen de Arrixaca University Hospital, Infectious Diseases Unit 30100 Espinardo, Murcia, Spain aut Cardona J. L. Hernández Microbiology Unit 30100 Espinardo, Murcia, Spain aut Núñez M. L. Microbiology Unit 30100 Espinardo, Murcia, Spain aut Gómez J. Ruiz Microbiology Unit 30100 Espinardo, Murcia, Spain aut Canteras M. Department of Biostatistics, School of Medicine, University of Murcia 30100 Espinardo, Murcia, Spain aut Valdés M. Department of Medicine, School of Medicine, University of Murcia 30100 Espinardo, Murcia, Spain aut Journal of Antimicrobial Chemotherapy Oxford University Press 38/2(1996-08), 309-314 0305-7453 38:2<309 1996 38 jac https://doi.org/10.1093/jac/38.2.309 text/html Onlinezugriff via DOI 1 other jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/38.2.309 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gómez J. Virgen de Arrixaca University Hospital, Infectious Diseases Unit 30100 Espinardo, Murcia, Spain aut NATIONALLICENCE 700 1- Cavero S. J. Conde Virgen de Arrixaca University Hospital, Infectious Diseases Unit 30100 Espinardo, Murcia, Spain aut NATIONALLICENCE 700 1- Cardona J. L. Hernández Microbiology Unit 30100 Espinardo, Murcia, Spain aut NATIONALLICENCE 700 1- Núñez M. L. Microbiology Unit 30100 Espinardo, Murcia, Spain aut NATIONALLICENCE 700 1- Gómez J. Ruiz Microbiology Unit 30100 Espinardo, Murcia, Spain aut NATIONALLICENCE 700 1- Canteras M. Department of Biostatistics, School of Medicine, University of Murcia 30100 Espinardo, Murcia, Spain aut NATIONALLICENCE 700 1- Valdés M. Department of Medicine, School of Medicine, University of Murcia 30100 Espinardo, Murcia, Spain aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 38/2(1996-08), 309-314 0305-7453 38:2<309 1996 38 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford