caa a22 4500 397592698 CHVBK 20180308164943.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.1093/jac/37.suppl_B.97 doi (NATIONALLICENCE)oxford-10.1093/jac/37.suppl_B.97 Wood M. J. Department of Infection and Tropical Medicine, Birmingham Heartlands Hospital, Birmingham B9 5SS, UK Antivirals in the context of HIV disease [Elektronische Daten] [M. J. Wood] Antiviral drugs, other than those with anti-retroviral activity, are used in persons with human immunodeficiency virus (HIV) infection for two purposes: treatment or prevention of viral infections that cause disease in persons with immunodeficiency, and to suppress viruses that might act as co-factors and promote replication of HIV itself. Human herpesviruses are the major targets of therapy in both settings. The herpesviruses, particularly cytomegalovirus (CMV), herpes simplex virus (HSV) and varicella-zoster virus (VZV) act as opportunistic pathogens as cell-mediated immunity declines, and there is theorectical, in-vitro, and in-vivo evidence that one or more herpesviruses can accelerate the progression of HIV disease. Therapy and prophylaxis with antiherpes compounds such as acyclovir, ganciclovir and foscarnet are well established in HIV infection, and this article will review their present use and recent improvements in formulations and drug delivery. © 1996 The British Society for Antimicrobial Chemotherapy Articles nationallicence Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 97-112 0305-7453 37<97 1996 37 jac https://doi.org/10.1093/jac/37.suppl_B.97 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.suppl_B.97 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Wood M. J. Department of Infection and Tropical Medicine, Birmingham Heartlands Hospital, Birmingham B9 5SS, UK NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 97-112 0305-7453 37<97 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford