caa a22 4500 397593341 CHVBK 20180308164945.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.1093/jac/37.suppl_B.151 doi (NATIONALLICENCE)oxford-10.1093/jac/37.suppl_B.151 Whitley Richard J. University of Alabama at Birmingham, Departments of Pediatrics, Microbiology, and Medicine, 616 Children's Hospital, 1600 Seventh Avenue South, Birmingham, AL 35233, USA Drug discovery for human immunodeficiency virus infection: conquests and hurdles [Elektronische Daten] [Richard J. Whitley] Drug development for the treatment of human immunodeficiency virus infection arena has been characterised by both successes and failures. The nucleoside reverse transcriptase inhibitors have been the major development for the management of the Acquired Immune Deficiency Disease Syndrome (AIDS); there has been a notable lack of licensed compounds directed at sites other than reverse transcriptase. In the development of drugs for the treatment of HIV infection, numerous tensions can be identified which need to be addressed to permit successful drug development in the future. These tensions include inherent conflicts between industry, government, regulatory authorities, academicians, and patients and as such need to be identified, discussed, and constructive solutions developed. © 1996 The British Society for Antimicrobial Chemotherapy Articles nationallicence Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 151-159 0305-7453 37<151 1996 37 jac https://doi.org/10.1093/jac/37.suppl_B.151 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.suppl_B.151 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Whitley Richard J. University of Alabama at Birmingham, Departments of Pediatrics, Microbiology, and Medicine, 616 Children's Hospital, 1600 Seventh Avenue South, Birmingham, AL 35233, USA NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 151-159 0305-7453 37<151 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford