caa a22 4500 39759383X CHVBK 20180308164946.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.1093/jac/37.suppl_A.73 doi (NATIONALLICENCE)oxford-10.1093/jac/37.suppl_A.73 Sparfloxacin for the treatment of community-acquired pneumonia: a pooled data analysis of two studies [Elektronische Daten] [M. Aubier, H. Lode, G. Gialdroni-Grassi, G. Huchon, J. Hosie, N. Legakis, C. Regamey, S. Segev, R. Vester, W. J. Wijnands, N. Tolstuchow] A pooled data analysis of two double-blind studies encompassing 1137 episodes of community-acquired pneumonia in hospitalised adults, of which 560 were treated with sparfloxacin and 577 were randomised to comparator antibacterial agents (amoxycillin/clavulanic acid, erythromycin or amoxycillin administered at reference dosages), was performed. The global efficacy rate at the end of treatment in evaluable patients treated with sparfloxacin was 88.3% compared with 84.1% in those who received comparator antibacterial agents. This analysis verified the efficacy of this new aminofluoroquinolone, given orally once daily, in the treatment of community acquired pneumonia. The overall outcome favoured sparfloxacin for use in the empirical treatment of community-acquired pneumonia. © 1996 The British Society for Antimicrobial Chemotherapy Articles nationallicence Aubier M. Hôpital Bichat 8° SUD. Service de Pneumologie 46 Rue Henri Huchard, 75018 Paris, France aut Lode H. Krankenhaus Zehlendorf, Chefartz Pneumologischen Abteilung 1 Zum Heckershom 33, 1000 Berlin 39, Germany aut Gialdroni-Grassi G. Universita di Pavia, Facolta di Medicina e Chirurgia, Cattedra di Chemoterapia Via Taramelli 5, 27100 Pavia, Italy aut Huchon G. Hopital Amboise Pare, Service de Pneumologie 9 Avenue Charles de Gaulle, 92104 Baulogne Billancourt, France aut Hosie J. Great Western Hospital 1980 Great Western Road, Glasgow G13 2SW, UK aut Legakis N. University of Athens, Microbiology Department 27 Navarinou Street, Cholargos, Athens 15562, Greece aut Regamey C. Hopital Cantonal, Service de Médecine, 1708 Fribourg, Switzerland aut Segev S. Sheba Medical Center, Infectious Diseases Center Tal Ashomer 52621, Israel aut Vester R. Leslie Williams Memorial Hospital Private Bag X2011, Carletonville 2500, South Africa aut Wijnands W. J. Stichling Deventer Ziekenhuizen PO Box 5001, 7400 GC Deventer, The Netherlands aut Tolstuchow N. Hôpital Hotel Dieu, Service des Urgences 4 rue Larrey, 49033 Angers, France aut Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 73-82 0305-7453 37<73 1996 37 jac https://doi.org/10.1093/jac/37.suppl_A.73 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.suppl_A.73 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Aubier M. Hôpital Bichat 8° SUD. Service de Pneumologie 46 Rue Henri Huchard, 75018 Paris, France aut NATIONALLICENCE 700 1- Lode H. Krankenhaus Zehlendorf, Chefartz Pneumologischen Abteilung 1 Zum Heckershom 33, 1000 Berlin 39, Germany aut NATIONALLICENCE 700 1- Gialdroni-Grassi G. Universita di Pavia, Facolta di Medicina e Chirurgia, Cattedra di Chemoterapia Via Taramelli 5, 27100 Pavia, Italy aut NATIONALLICENCE 700 1- Huchon G. Hopital Amboise Pare, Service de Pneumologie 9 Avenue Charles de Gaulle, 92104 Baulogne Billancourt, France aut NATIONALLICENCE 700 1- Hosie J. Great Western Hospital 1980 Great Western Road, Glasgow G13 2SW, UK aut NATIONALLICENCE 700 1- Legakis N. University of Athens, Microbiology Department 27 Navarinou Street, Cholargos, Athens 15562, Greece aut NATIONALLICENCE 700 1- Regamey C. Hopital Cantonal, Service de Médecine, 1708 Fribourg, Switzerland aut NATIONALLICENCE 700 1- Segev S. Sheba Medical Center, Infectious Diseases Center Tal Ashomer 52621, Israel aut NATIONALLICENCE 700 1- Vester R. Leslie Williams Memorial Hospital Private Bag X2011, Carletonville 2500, South Africa aut NATIONALLICENCE 700 1- Wijnands W. J. Stichling Deventer Ziekenhuizen PO Box 5001, 7400 GC Deventer, The Netherlands aut NATIONALLICENCE 700 1- Tolstuchow N. Hôpital Hotel Dieu, Service des Urgences 4 rue Larrey, 49033 Angers, France aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37(1996-05), 73-82 0305-7453 37<73 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford