caa a22 4500 397593856 CHVBK 20180308164946.0 cr unu---uuuuu 161202e199610 xx s 000 0 eng 10.1093/jac/38.4.579 doi (NATIONALLICENCE)oxford-10.1093/jac/38.4.579 The effects of antifungal agents on the morphogenetic transformation by Candida albicans in vitro [Elektronische Daten] [Stephen Hawser, Maura Francolini, Khalid Islam] The effects of antifungal agents, with different mechanisms of action, on the morphogenetic transformation by synchronised yeast-phase Candida albicans cells in vitro and their respective anti-Candida activities are described. MIC data demonstrated that the azoles, amphotericin B and echinocandin were the most active agents against four C. albicans strains. Morphogenetic transformation experiments demonstrated that amphotericin B was significantly better at preventing the transformation, under a variety of test conditions, than the azoles and flucytosine: amphotericin B abolished the transformation at low concentrations while the azoles only prevented the morphogenetic transformation at much higher concentrations (>100 × MIC). © 1995 The British Society for Antimicrobial Chemotherapy Original articles nationallicence Hawser Stephen Lepetit Research Center, Marion Merrell Dow Research Institute Via R. Lepetit 34, 21040 Gerenzano (Varese) aut Francolini Maura Department of Biology, University of Milan Via Celoria 26, 20133 Milan, Italy aut Islam Khalid Lepetit Research Center, Marion Merrell Dow Research Institute Via R. Lepetit 34, 21040 Gerenzano (Varese) aut Journal of Antimicrobial Chemotherapy Oxford University Press 38/4(1996-10), 579-587 0305-7453 38:4<579 1996 38 jac https://doi.org/10.1093/jac/38.4.579 text/html Onlinezugriff via DOI 1 other jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/38.4.579 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hawser Stephen Lepetit Research Center, Marion Merrell Dow Research Institute Via R. Lepetit 34, 21040 Gerenzano (Varese) aut NATIONALLICENCE 700 1- Francolini Maura Department of Biology, University of Milan Via Celoria 26, 20133 Milan, Italy aut NATIONALLICENCE 700 1- Islam Khalid Lepetit Research Center, Marion Merrell Dow Research Institute Via R. Lepetit 34, 21040 Gerenzano (Varese) aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 38/4(1996-10), 579-587 0305-7453 38:4<579 1996 38 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford