caa a22 4500 397593899 CHVBK 20180308164947.0 cr unu---uuuuu 161202e199605 xx s 000 0 eng 10.1093/jac/37.5.1005 doi (NATIONALLICENCE)oxford-10.1093/jac/37.5.1005 In-vitro activity of psychiatric drugs against Corynebacterium urealyticum (Corynebacterium group D2) [Elektronische Daten] [J. L. Muñioz-Bellido, S. Muñioz-Bellido, J. A. García-Rodrfguez] We tested the in-vitro activity of amoxycillin, amoxycillin/clavulanic acid, cefotaxime, gentamicin, trimethoprim-sulphamethoxazole, tetracycline, norfloxacin, ciprofloxacin, vancomycin, teicoplanin, clindamycin and five psychiatric drugs (chlorpromazirje, sertraline, fluoxetine, paroxetine and risperidone) against 32 strains of Corynebacterium urealyticum. Resistance rates exceeded 90% for all antibiotics except glycopeptides, quinolones and tetracycline. Sertraline was the most active psychiatric drug. We tested the influence of sertraline on the activity of amoxycillin, amoxycillin/clavulanic acid, cefotaxime, gentamicin, trimethoprim-sulphamethoxazole, tetracycline and ciprofloxacin. We did not observe antagonism in any case. Sertraline enhanced the activity of ciprofloxacin and tetracycline against all strains (MIC decrease: 4-64-fold for ciprofloxacin, 2-32-fold for tetracycline). © 1996 The British Society for Antimicrobial Chemotherapy Brief reports nationallicence Muñioz-Bellido J. L. Departamento de Microbiologia y Parasitologia, Hospital Universitario de Salamanca, Paseo de San Vicente 108, 37007 Salamanca, Spain aut Muñioz-Bellido S. Departamento de Microbiologia y Parasitologia, Hospital Universitario de Salamanca, Paseo de San Vicente 108, 37007 Salamanca, Spain aut García-Rodrfguez J. A. Departamento de Microbiologia y Parasitologia, Hospital Universitario de Salamanca, Paseo de San Vicente 108, 37007 Salamanca, Spain aut Journal of Antimicrobial Chemotherapy Oxford University Press 37/5(1996-05), 1005-1009 0305-7453 37:5<1005 1996 37 jac https://doi.org/10.1093/jac/37.5.1005 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1093/jac/37.5.1005 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Muñioz-Bellido J. L. Departamento de Microbiologia y Parasitologia, Hospital Universitario de Salamanca, Paseo de San Vicente 108, 37007 Salamanca, Spain aut NATIONALLICENCE 700 1- Muñioz-Bellido S. Departamento de Microbiologia y Parasitologia, Hospital Universitario de Salamanca, Paseo de San Vicente 108, 37007 Salamanca, Spain aut NATIONALLICENCE 700 1- García-Rodrfguez J. A. Departamento de Microbiologia y Parasitologia, Hospital Universitario de Salamanca, Paseo de San Vicente 108, 37007 Salamanca, Spain aut NATIONALLICENCE 773 0- Journal of Antimicrobial Chemotherapy Oxford University Press 37/5(1996-05), 1005-1009 0305-7453 37:5<1005 1996 37 jac Metadata rights reserved CC BY-NC-4.0 http://creativecommons.org/licenses/by-nc/4.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-oxford